A rare case of ulcerative colitis exacerbated by VZV infection

被引：2
|
作者：
Nishimura S. [1 ]
Yoshino T. [1 ]
Fujikawa Y. [1 ]
Watanabe M. [1 ]
Yazumi S. [1 ]
机构：
[1] Division of Gastroenterology and Hepatology, Digestive Disease Center, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimach, Kita-ku, Osaka
来源：
Clinical Journal of Gastroenterology | 2015年 / 8卷 / 6期
基金：
日本学术振兴会;
关键词：
Aciclovir; Ulcerative colitis; Varicella-zoster virus;
D O I：
10.1007/s12328-015-0613-8
中图分类号：
学科分类号：
摘要：
A 16-years old man with severe ulcerative colitis (UC) was admitted to our hospital. After initiating treatment with corticosteroid for UC, chicken pox appeared. At the same time of appearance of chicken pox, the disease activity of UC was exacerbated. After initiating the treatment with acyclovir, both chicken pox and UC improved. Because colonoscopic findings revealed the remaining of moderately active UC, initiating the treatment with infliximab could induce clinical remission of UC without relapse of varicella-zoster virus (VZV) infection. This is a very rare case of UC with concomitant VZV infection. According to our report, the vaccination for VZV prior to immunosuppressive treatments would be necessary for VZV naïve patients with UC. © 2015, Japanese Society of Gastroenterology.
引用
收藏
页码：390 / 392
页数：2
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