Antitumor activity of TY-011 against gastric cancer by inhibiting Aurora A, Aurora B and VEGFR2 kinases

被引：0

作者：

Wang Liu

Yu Lu

Xiaoping Chai

Xiao Liu

Tong Zhu

Xihan Wu

Yanfen Fang

Xuan Liu

Xiongwen Zhang

机构：

[1] East China Normal University,Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering

[2] Nanjing Tianyi Bioscience Co. Ltd,Department of Cardiology, Shanghai Renji Hospital, School of Medicine

[3] Shanghai Jiaotong University,School of Physics and Materials Science

[4] East China Normal University,undefined

来源：

Journal of Experimental & Clinical Cancer Research | / 35卷

关键词：

Gastric cancer; Cell cycle; Angiogenesis; Polyploidy; Apoptosis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 20 条

[1] Antitumor activity of TY-011 against gastric cancer by inhibiting Aurora A, Aurora B and VEGFR2 kinases
Liu, Wang
Lu, Yu
Chai, Xiaoping
Liu, Xiao
Zhu, Tong
Wu, Xihan
Fang, Yanfen
Liu, Xuan
Zhang, Xiongwen
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2016, 35 : 1 - 15
[2] Antitumor activity of a novel Aurora A/B kinases inhibitor TY-011 against gastric cancer by inducing DNA damage
Jiang Tongtong
Liu Wang
Lu Yu
Fang Yanfen
Chen Rui
Zhang Wanli
Liu Xuan
Zhang Xiongwen
ANTI-CANCER DRUGS, 2020, 31 (05) : 440 - 451
[3] Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases
Kai, Kazuharu
Kondo, Kimie
Wang, Xiaoping
Xie, Xuemei
Pitner, Mary K.
Reyes, Monica E.
Torres-Adorno, Angie M.
Masuda, Hiroko
Hortobagyi, Gabriel N.
Bartholomeusz, Chandra
Saya, Hideyuki
Tripathy, Debu
Sen, Subrata
Ueno, Naoto T.
MOLECULAR CANCER THERAPEUTICS, 2015, 14 (12) : 2687 - 2699
[4] The Aurora A and Aurora B protein kinases - A single amino acid difference controls intrinsic activity and activation by TPX2
Eyers, PA
Churchill, MEA
Maller, JL
CELL CYCLE, 2005, 4 (06) : 784 - 789
[5] Immune-Mediated Antitumor Effect By VEGFR2 Selective Inhibitor For Gastric Cancer
Yang, Ju
Yan, Jing
Shao, Jie
Xu, Qiuping
Meng, Fanyan
Chen, Fangjun
Ding, Naiqing
Du, Shiyao
Zhou, Shujuan
Cai, Juan
Wang, Qin
Liu, Baorui
ONCOTARGETS AND THERAPY, 2019, 12 : 9757 - 9765
[6] Characterization and risk association of polymorphisms in Aurora kinases A, B and C with genetic susceptibility to gastric cancer development
Aner Mesic
Marija Rogar
Petra Hudler
Nurija Bilalovic
Izet Eminovic
Radovan Komel
BMC Cancer, 19
[7] Characterization and risk association of polymorphisms in Aurora kinases A, B and C with genetic susceptibility to gastric cancer development
Mesic, Aner
Rogar, Marija
Hudler, Petra
Bilalovic, Nurija
Eminovic, Izet
Komel, Radovan
BMC CANCER, 2019, 19 (01)
[8] A thienopyrimidine derivative induces growth inhibition and apoptosis in human cancer cell lines via inhibiting Aurora B kinase activity
Li, Jie
Hu, Hairong
Lang, Qingyu
Zhang, Haoxing
Huang, Qiang
Wu, Yuanyuan
Yu, Long
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 65 : 151 - 157
[9] Potent antitumor activity of cabozantinib, a c- MET and VEGFR2 inhibitor, in a colorectal cancer patient- derived tumor explant model
Song, Eun-Kee
Tai, W. M.
Messersmith, Wells A.
Bagby, Stacey
Purkey, Alicia
Quackenbush, Kevin S.
Pitts, Todd M.
Wang, Guoliang
Blatchford, Patrick
Yahn, Rachel
Kaplan, Jeffrey
Tan, Aik Choon
Atreya, Chloe E.
Eckhardt, Gail
Kelley, Robin K.
Venook, Alan
Kwak, Eunice L.
Ryan, David
Arcaroli, John J.
INTERNATIONAL JOURNAL OF CANCER, 2015, 136 (08) : 1967 - 1975
[10] Abnormal phenotype of Nrf2 is associated with poor prognosis through hypoxic/VEGF-A-Rap1b/VEGFR2 pathway in gastric cancer
Yang, Ya
Wang, Xin
Zhang, Jia
Gu, Hao
Zhang, Song
Sun, Hao
Liu, Junqi
Fan, Ruitai
AGING-US, 2022, 14 (07): : 3293 - 3312

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