Development of biosensor for detection of serum creatinine

被引:8
作者
Pallavi Dasgupta
Vinay Kumar
P. R. Krishnaswamy
Navakanta Bhat
机构
[1] Indian Institute of Science,Centre for Nanoscience and Engineering (CeNSE)
[2] Indian Institute of Science,PathShodh Healthcare
关键词
Chronic kidney disease; Electrochemical biosensor; Serum creatinine; Point-of-care technology (POCT);
D O I
10.1007/s40012-018-0187-y
中图分类号
学科分类号
摘要
Serum creatinine is an established biochemical marker for monitoring of renal function. Analytical methods to detect creatinine concentration have been investigated as early as 1886. However, majority of these methods involve sophisticated instrumentation which limits its accessibility to economically challenged patients. In this regard, point of care biosensors provide a low-cost solution coupled with simple instrumentation. There has been growing interest in development of point-of-care technology (POCT) devices for creatinine estimation. However, majority of these POCT devices are enzymatic assays, which add to the complexity and the cost. In this work, we aim to develop non-enzymatic electrochemical creatinine biosensor which simplifies the process of routine clinical analysis, and thereby making it accessible due to its low-cost.
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页码:5 / 10
页数:5
相关论文
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