Regulatory Role of Na,K-ATPase in the Growth of Heart Tissue Explants in Organotypic Culture

被引:0
作者
E. V. Lopatina
V. A. Penniyainen
A. A. Zaika
机构
[1] Russian Ministry of Health,V. A. Almazov Institute of Cardiology
[2] I. P. Pavlov Institute of Physiology,undefined
来源
Bulletin of Experimental Biology and Medicine | 2005年 / 140卷
关键词
Na; K-ATPase; signal transducer; organotypic tissue culture; α; isoform;
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学科分类号
摘要
We studied the effects of ouabain, norepinephrine, and acetylcholine on the growth of heart tissue explants from 10–12-old chicken embryos in an organotypic culture. Ouabain, norepinephrine, and acetylcholine stimulated the growth of explants. Our results suggest that trophic function of acetylcholine and norepinephrine is associated with regulation of Na,K-ATPase activity as a signal transducer.
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页码:184 / 186
页数:2
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