Chronic nicotine pretreatment is sufficient to upregulate α4* nicotinic receptors and increase oral nicotine self-administration in mice

[11] De Biasi M(2012)Ventral tegmental area glutamate neurons: electrophysiological properties and projections J Neurosci 32 15076-15085

[12] Tapper AR(1992)The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine Psychopharmacology (Berl) 107 285-289

[13] McKinney SL(2002)Lesions of the tegmental pedunculopontine nucleus block the rewarding effects and reveal the aversive effects of nicotine in the ventral tegmental area J Neurosci 22 8653-8660

[14] Nashmi R(2006)Genetic dissociation of two behaviors associated with nicotine addiction: beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome Psychopharmacology (Berl) 187 189-199

[15] Schwarz J(2008)Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration J Neurosci 28 12318-12327

[16] Deshpande P(1999)Effects of continuous oral nicotine administration on brain nicotinic receptors and responsiveness to nicotine in C57Bl/6 mice Psychopharmacology (Berl) 141 145-153

[17] Labarca C(1983)Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo Science 220 214-216

[18] Whiteaker P(1988)Evidence that tobacco smoking increases the density of (−)-[3H]nicotine binding sites in human brain J Neurochem 50 1243-1247

[19] Marks MJ(1999)Increased nicotinic receptors in brains from smokers: membrane binding and autoradiography studies J Pharmacol Exp Ther 289 1545-1552

[20] Collins AC(2005)Nicotine physical dependence and tolerance in the mouse following chronic oral administration Psychopharmacology (Berl) 178 183-192

[11] De Biasi M(2012)Ventral tegmental area glutamate neurons: electrophysiological properties and projections J Neurosci 32 15076-15085

[12] Tapper AR(1992)The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine Psychopharmacology (Berl) 107 285-289

[13] McKinney SL(2002)Lesions of the tegmental pedunculopontine nucleus block the rewarding effects and reveal the aversive effects of nicotine in the ventral tegmental area J Neurosci 22 8653-8660

[14] Nashmi R(2006)Genetic dissociation of two behaviors associated with nicotine addiction: beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome Psychopharmacology (Berl) 187 189-199

[15] Schwarz J(2008)Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration J Neurosci 28 12318-12327

[16] Deshpande P(1999)Effects of continuous oral nicotine administration on brain nicotinic receptors and responsiveness to nicotine in C57Bl/6 mice Psychopharmacology (Berl) 141 145-153

[17] Labarca C(1983)Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo Science 220 214-216

[18] Whiteaker P(1988)Evidence that tobacco smoking increases the density of (−)-[3H]nicotine binding sites in human brain J Neurochem 50 1243-1247

[19] Marks MJ(1999)Increased nicotinic receptors in brains from smokers: membrane binding and autoradiography studies J Pharmacol Exp Ther 289 1545-1552

[20] Collins AC(2005)Nicotine physical dependence and tolerance in the mouse following chronic oral administration Psychopharmacology (Berl) 178 183-192