Chronic nicotine pretreatment is sufficient to upregulate α4* nicotinic receptors and increase oral nicotine self-administration in mice

[1] Jha P(2013)21st-century hazards of smoking and benefits of cessation in the United States N Engl J Med 368 341-350

[2] Ramasundarahettige C(2004)Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit J Neurosci 24 10035-10039

[3] Landsman V(2004)Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization Science 306 1029-1032

[4] Rostron B(1998)Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine Nature 391 173-177

[5] Thun M(2005)Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors Nature 436 103-107

[6] Anderson RN(1992)Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment J Neurosci 12 2765-2784

[7] McAfee T(2007)Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path J Neurosci 27 8202-8218

[8] Peto R(1987)Structurally different neuronal nicotinic acetylcholine receptor subtypes purified and characterized using monoclonal antibodies J Neurosci 7 4005-4016

[9] Salas R(1996)Preferential activation of midbrain dopamine neurons by appetitive rather than aversive stimuli Nature 379 449-451

[10] Pieri F(2003)Blockade of mesolimbic dopamine transmission dramatically increases sensitivity to the rewarding effects of nicotine in the ventral tegmental area Mol Psychiatry 8 50-59

[1] Jha P(2013)21st-century hazards of smoking and benefits of cessation in the United States N Engl J Med 368 341-350

[2] Ramasundarahettige C(2004)Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit J Neurosci 24 10035-10039

[3] Landsman V(2004)Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization Science 306 1029-1032

[4] Rostron B(1998)Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine Nature 391 173-177

[5] Thun M(2005)Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors Nature 436 103-107

[6] Anderson RN(1992)Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment J Neurosci 12 2765-2784

[7] McAfee T(2007)Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path J Neurosci 27 8202-8218

[8] Peto R(1987)Structurally different neuronal nicotinic acetylcholine receptor subtypes purified and characterized using monoclonal antibodies J Neurosci 7 4005-4016

[9] Salas R(1996)Preferential activation of midbrain dopamine neurons by appetitive rather than aversive stimuli Nature 379 449-451

[10] Pieri F(2003)Blockade of mesolimbic dopamine transmission dramatically increases sensitivity to the rewarding effects of nicotine in the ventral tegmental area Mol Psychiatry 8 50-59