Synthesis of alkyl 4-(1-alkyl-2-aryl-2-oxoethyl)-5,5-dimethyl-2- oxotetrahydrofuran-3-carboxylates and their reactions with amines

被引：0

作者：

Shchepin V.V. ^{[1
]}

Korzun A.E. ^{[1
]}

Bronnikova N.V. ^{[1
]}

机构：

[1] Perm State University, ul. Bukireva 15, Perm

来源：

Russian Journal of Organic Chemistry | 2004年 / 40卷 / 7期

关键词：

Zinc; Organic Chemistry; Piperidine; Enolates; Carboxamides;

D O I：

10.1023/B:RUJO.0000045192.57169.4e

中图分类号：

学科分类号：

摘要：

Zinc enolates derived from 1-aryl-2-bromoalkanones react with alkyl 5,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylates to give alkyl 4-(1-alkyl-2-aryl-2-oxoethyl)-5,5-dimethyl-2-oxotetrahydrofuran-3-carboxylates. Reactions of the latter with amines, such as p-toluidine, cyclohexylamine, and piperidine, lead to the corresponding carboxamides.

引用

页码：998 / 1002

页数：4