Responses of respiratory neurons in the medulla oblongata to stimulation of the septal nuclei during hypoxia

被引：0

作者：

Akopyan N.S. ^{[1
]}

Adamyan N.Yu. ^{[1
]}

Sarkisyan N.V. ^{[1
]}

Arutyunyan R.S. ^{[1
]}

机构：

[1] Dept. of Human/Animal Physiology, Armenian State University, 375049 Erevan

来源：

Neuroscience and Behavioral Physiology | 2004年 / 34卷 / 1期

关键词：

Hypoxia; Respiratory center; Septum; Spike activity;

D O I：

10.1023/B:NEAB.0000003254.69342.6e

中图分类号：

学科分类号：

摘要：

Dynamic studies were performed in conditions of hypoxia on the effects of stimulation of the ventral, lateral, and medial nuclei of the septum on the spike activity of bulbar respiratory neurons and respiration. The various phases of hypoxia provided a model experiment over which the overall effects of the septal neurons were summed. Electrical stimulation of these septal nuclei in conditions of normal atmospheric pressure had both facilitatory and inhibitory effects on the spike activity of respiratory neurons in the respiratory center of the medulla oblongata, inhibitory effects being predominant. The ventral nucleus had the most effective inhibitory effect on the activity of respiratory neurons. Electrical stimulation of the septal nuclei in the initial phase (4000-5000 m) of hypoxia, on the background of activation, had a predominantly inhibitory influence on the activity of respiratory neurons. During the phase of severe hypoxia (7500-8000 m), on the background of marked hypoxic suppression of respiratory neuron activity, stimulation of the septal nuclei produced no characteristic changes in the activity of these neurons. © 2004 Plenum Publishing Corporation.

引用

页码：105 / 108

页数：3

共 19 条

[1]

Akopyan N.S., Baklavadzhyan O.G., Sarkisyan N.V., Responses of medulla oblongata respiratory neurons to stimulation of the nuclei of the amygdaloid complex in hypoxia, Fiziol. Zh. SSSR, 77, 12, pp. 41-49, (1991)

[2]

Baklavadzhyan O.G., Neuronal Organization of the Amygdalo-Visceral Reflex Arc, (1996)

[3]

Buresh Ya., Petran M., Zakhar I., Electrophysiological Study Methods, (1962)

[4]

Val'dman A.V., Neuropharmacology of Central Regulatory Processes, (1969)

[5]

Vlasova I.G., The nerve cell and hypoxia, Proceedings of the VII International Symposium "Ecological-Physiological Problems of Adaptation, (1994)

[6]

Karapetyan M.A., Akopyan N.S., Baklavadzhyan O.G., Studies of the hypothalamic mechanism of regulation of respiratory neuron activity in the medulla oblongata in conditions of hypoxia, Fiziol. Zh. SSSR, 13, 7, (1987)

[7]

Koval' I.N., Sarkisov G.T., Gambaryan L.S., The Septohippocampal System and the Organization of Behavior, (1986)

[8]

Nersesyan L.B., Baklavadzhyan O.G., Eganova V.S., Armakyan A.V., Pogosyan N.L., Sarukhanyan R.V., The role of septal structures in controlling the activity of bulbar respiratory neurons and sympathetic nerves, Arkh. Klin. Éksper. Med., 9, 1, (2000)

[9]

Oivin I.A., Statistical analysis of experimental data, Patol. Fiziol. Éksper. Ter., 4, 4, pp. 76-85, (1959)

[10]

Samoilov M.O., The Responses of Brain Neurons to Hypoxia, (1985)

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