Foreseeing the principles of genome architecture

被引:0
作者
Tom Misteli
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[1] National Cancer Institute,
[2] National Institutes of Health,undefined
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摘要
Tom Misteli highlights a 2006 study by Shopland et al., which used relatively simple methods to visualize characteristics of chromosome organization. Their conclusions foreshadowed key concepts in the field: topologically associating domains, compartments and cell-to-cell heterogeneity in genome organization.
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相关论文
共 2 条
[1]  
Shopland LS(2006)Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence J. Cell Biol. 174 27-38
[2]  
Misteli T(2020)The self-organizing genome: principles of genome organization and function Cell 183 28-45