Exocellular Peptides from Antarctic PsychrophilePseudoalteromonas Haloplanktis

被引：0
|
作者：
Maya Mitova
Maria Luisa Tutino
Giuseppe Infusini
Gennaro Marino
Salvatore De Rosa
机构：
[1] Istituto di Chimica Biomolecole CNR,
[2] Institute of Organic Chemistry with Center of Phytochemistry,undefined
[3] Dipartimento di Chimica Organica e Biochimica Università di Napoli Federico II,undefined
来源：
Marine Biotechnology | 2005年 / 7卷
关键词：
marine bacteria; cyclodipeptides; peptides;
D O I：
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中图分类号：
学科分类号：
摘要：
A novel diketopiperazine, named cyclo-(D-pipecolinyl-L-isoleucine) (DKP 1), and 7 known diketopiperazines were isolated from the cell-free culture supernatant of the Antarctic psychrophilic bacterium Pseudoalteromonas haloplanktis TAC125. Two diketopiperazines containing pipecolinyl moiety were isolated for the first time from a natural source. Two new linear peptides, stable to bacterial proteolytic enzymes, were also characterized. The structures of the isolated compounds were elucidated by means of spectroscopic data (1D-, 2D-NMR, EIMS, FABMS, and ESIMS/MS) and chiral high-performance liquid chromatography. The potential antioxidant activity of the isolated compounds was evaluated by a DPPH free radical scavenging assay.
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页码：523 / 531
页数：8
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