Calorimetric studies of the interactions between micelle-forming and bilayer-forming amphiphiles

We develop a theoretical basis for detailed investigations of mixed aqueous solutions of amphiphiles by high resolution titration calorimetry (ITC). We review the phenomenology of phase behavior of these systems and formulate the questions addressed in thermodynamic studies. Based on the equations obtained, we introduce a general scheme of calorimetric measurements allowing to characterize comprehensively the energetics of the mixtures. We discuss the results of previous studies in relation to this scheme.