Aliskiren prevents cardiovascular complications and pancreatic injury in a mouse model of obesity and type 2 diabetes

被引:0
作者
Y. F. Dong
L. Liu
K. Kataoka
T. Nakamura
M. Fukuda
Y. Tokutomi
H. Nako
H. Ogawa
S. Kim-Mitsuyama
机构
[1] Kumamoto University Graduate School of Medical Sciences,Department of Pharmacology and Molecular Therapeutics
[2] Kumamoto University Graduate School of Medical Sciences,Department of Cardiovascular Medicine
来源
Diabetologia | 2010年 / 53卷
关键词
Aliskiren; Cardiovascular complications; Insulin resistance; Oxidative stress;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:180 / 191
页数:11
相关论文
共 145 条
[1]  
Alderman MH(1999)Diabetes and cardiovascular events in hypertensive patients Hypertension 33 1130-1134
[2]  
Cohen H(2003)Follow-up report on the diagnosis of diabetes mellitus Diabetes Care 26 3160-3167
[3]  
Madhavan S(1993)Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial Diabetes Care 16 434-444
[4]  
Genuth S(2004)Adverse prognostic significance of new diabetes in treated hypertensive subjects Hypertension 43 963-969
[5]  
Alberti KG(2000)Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators N Engl J Med 342 145-153
[6]  
Bennett P(2005)Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers for prevention of type 2 diabetes: a meta-analysis of randomized clinical trials J Am Coll Cardiol 46 821-826
[7]  
Stamler J(2002)Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint Reduction in Hypertension Study (LIFE): a randomised trial against atenolol Lancet 359 995-1003
[8]  
Vaccaro O(2004)Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial Lancet 363 2022-2031
[9]  
Neaton JD(2004)Renin–angiotensin system and angiotensin receptor blockers in the metabolic syndrome Circulation 110 1507-1512
[10]  
Wentworth D(2008)Aliskiren Circulation 118 773-784