Expression of thymidylate synthase determines the response of gastric cancer patients undergoing gastrectomy to 5-fluorouracil-based adjuvant chemotherapy

被引:0
作者
Chun-Nan Yeh
Shih-Ming Jung
Tsung-Wen Chen
Tsann-Long Hwang
Yi-Yin Jan
Miin-Fu Chen
机构
[1] Chang Gung Memorial Hospital,Department of Pathology
[2] Chang Gung University,Department of Surgery
[3] Chang Gung Memorial Hospital,undefined
[4] Chang Gung University,undefined
来源
Langenbeck's Archives of Surgery | 2010年 / 395卷
关键词
Thymidylate synthase; Gastric cancer; Gastrectomy; Adjuvant chemotherapy;
D O I
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页码:217 / 225
页数:8
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  • [21] Fattori PP(1998)Biological markers as a predictor for response and prognosis of unresectable gastric cancer patients treated with 5-fluorouracil and cis-platinum Clin Cancer Res. 4 1469-1474
  • [22] Macdonald JS(1998)High expression of thymidylate synthase is associated with the drug resistance of gastric carcinoma to high dose 5-fluorouracil-based systemic chemotherapy Cancer 82 1626-1631
  • [23] Smalley SR(2005)Prognostic role of thymidylate synthase polymorphisms in gastric cancer patients treated with surgery and adjuvant chemotherapy Clin Cancer Res 11 3778-3783
  • [24] Benedetti J(1998)Immunohistochemical evaluation of thymidylate synthase in gastric carcinoma using a new polyclonal antibody: the clinical role of thymidylate synthase as a prognostic indicator and its therapeutic usefulness Cancer 83 1300-1306
  • [25] Cunningham D(1999)Immunohistochemical detection of thymidylate synthase in advanced gastric cancer: a prognostic indicator in patients undergoing gastrectomy followed by adjuvant chemotherapy with 5-fluoropyrimidines Anticancer Res 19 805-810
  • [26] Allum WH(1992)Results of surgery on 6589 gastric cancer patients and immunochemosurgery as the best treatment of advanced gastric cancer Ann Surg 216 269-279
  • [27] Stenning SP(1994)Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer Lancet 343 1122-1126
  • [28] Hundahl SA(1996)Adjuvant and neoadjuvant therapy for gastric cancer Semin Oncol 23 379-389
  • [29] Macdonald JS(1996)The treatment of advanced gastric cancer Semin Oncol 23 397-406
  • [30] Benedetti J(1998)OK-432 and 5-fluorouracil, doxorubicin, and mitomycin C (FAM-P) versus FAM chemotherapy in patients with curatively resected gastric carcinoma: a randomized phase III trial Cancer 83 2054-2059