Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications

被引：0
作者：
Sakey Ravindra
Antoine F. Mulaba-Bafubiandi
V. Rajinikanth
K. Varaprasad
N. Narayana Reddy
K. Mohana Raju
机构：
[1] University of Johannesburg,Department of Chemical Engineering Technology, Faculty of Engineering and the Built Environment
[2] University of Johannesburg,Department of Metallurgy, Faculty of Engineering and the Built Environment
[3] Sri Krishnadevaraya University,Synthetic Polymer Laboratory, Department of Polymer Science & Technology
[4] University of Mons,Department of General, Organic and Biomedical Chemistry
来源：
Journal of Inorganic and Organometallic Polymers and Materials | 2012年 / 22卷
关键词：
Hydrogel network; Silver nanoparticles; Antibacterial activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The present work involves the development of curcumin loaded silver hydrogel nanocomposites based on acrylamide and 2-acrylamido-2-methyl propanesulfonic acid, as a template by redox co-polymerization in the presence of hydrophilic crosslinker N,N1-methylenebisacrylamide. Silver nitrate was taken as the metal precursor and sodium borohydride as a reducing agent. The formation of silver nanoparticles was monitored using UV–Vis absorption spectroscopy. The developed hydrogel silver nanocomposites (HSNC) were characterized by FTIR, UV–Vis, thermogravimetric analysis, scanning electron microscopy and transmission electron microscopy. The curcumin loading and release characteristics were performed for different hydrogel systems. The developed HSNCs were evaluated for preliminary antibacterial applications.
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页码：1254 / 1262
页数：8
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