Association between rare variants in specific functional pathways and human neural tube defects multiple subphenotypes

Shinotsuka N(2005)Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development Proc Natl Acad Sci U S A 102 4367-232

Nonomura K(2009)Mice defective in Trpm6 show embryonic mortality and neural tube defects Hum Mol Genet 18 1689-1222

Takemoto K(2009)Removal of maternal retinoic acid by embryonic CYP26 is required for correct nodal expression during early embryonic patterning Genes Dev 23 247-241

Kuida K(1999)DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development Cell 99 513-118

Yosida H(2005)CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L Hum Mol Genet 14 229-116

Miura M(2000)Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development Nat Genet 26 1211-1503

Holmberg J(1995)Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation Genes Dev 9 225-1778

Clarke DL(1981)Growth and development of pattern in the cranial neural epithelium of rat embryos during neurulation J Embryol Exp Morphol 65 97-2393

Frisen J(1983)An SEM analysis of neural crest migration in the mouse J Embryol Exp Morphol 74 106-1214

Pyrgaki C(2002)Tissue origins and interactions in the mammalian skull vault Dev Biol 241 1496-21

Shinotsuka N(2005)Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development Proc Natl Acad Sci U S A 102 4367-232

Nonomura K(2009)Mice defective in Trpm6 show embryonic mortality and neural tube defects Hum Mol Genet 18 1689-1222

Takemoto K(2009)Removal of maternal retinoic acid by embryonic CYP26 is required for correct nodal expression during early embryonic patterning Genes Dev 23 247-241

Kuida K(1999)DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development Cell 99 513-118

Yosida H(2005)CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L Hum Mol Genet 14 229-116

Miura M(2000)Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development Nat Genet 26 1211-1503

Holmberg J(1995)Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation Genes Dev 9 225-1778

Clarke DL(1981)Growth and development of pattern in the cranial neural epithelium of rat embryos during neurulation J Embryol Exp Morphol 65 97-2393

Frisen J(1983)An SEM analysis of neural crest migration in the mouse J Embryol Exp Morphol 74 106-1214

Pyrgaki C(2002)Tissue origins and interactions in the mammalian skull vault Dev Biol 241 1496-21