Tools in polypharmacy: Current evidence from observational and controlled studies; [Werkzeuge im Umgang mit Polypharmazie: Aktuelle Evidenz aus kontrollierten- und Beobachtungsstudien]

被引:0
作者
Dovjak P. [1 ]
机构
[1] Landeskrankenhaus Gmunden, 4810 Gmunden
关键词
Adverse drug events; Drug interactions; Geriatrics; Patient adherence; Polypharmacy;
D O I
10.1007/s00391-012-0362-y
中图分类号
学科分类号
摘要
Increasing evidence in managing polypharmacy in the growing elderly population with a higher prevalence of multiple chronic disease is the basis for this paper. Poor adherence, drug-drug interactions, drug-disease interactions, and inappropriate medication challenge the prescriptions of health care providers in this group of patients. Risk factors, the prevalence of polypharmacy, and the impact on health issues will be shown by analyzing the recent literature. Based on intervention trials, several tools in polypharmacy have emerged as practical guides for clinical practice or for the geriatric ward to solve this problem. The Medication Appropriateness Index (MAI) and national lists of potentially inappropriate medication used in clinical practice are presented, including Screening Tool to Alert Doctors to the Right Treatment (START), Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP), and Assess, Comprehensive Geriatric Assessment, Adherence, Development, Emergence, Minimization, Interdisciplinarity, Alertness (ACADEMIA). © Springer-Verlag 2012.
引用
收藏
页码:468 / 472
页数:4
相关论文
共 32 条
[1]  
Bain K.T., Holmes H.M., Beers M.H., Et al., Discontinuing medications: A novel approach for revising the prescribing stage of the medication-use process, J Am Geriatr Soc, 56, pp. 1946-1952, (2008)
[2]  
Barry P.J., Gallagher P., Ryan C., Et al., START (screening tool to alert doctors to the right treatment)an evidence-based screening tool to detect prescribing omissions in elderly patients, Age Ageing, 36, pp. 632-638, (2007)
[3]  
Campanielli C.M., The American Geriatrics Society. American Geriatrics Society updated Beers criteria for potentially inappropriate medication use in older adults, J Am Geriatr Soc, 60, pp. 616-631, (2012)
[4]  
Carey E.C., Covinsky K.E., Lui L.Y., Et al., Prediction of mortality in community-living frail elderly people with long-term care needs, J Am Geriatr Soc, 56, pp. 68-75, (2008)
[5]  
Chumney E.C., Robinson L.C., The effect of pharmacist interventions on patients with polyphamacy, Pharm Pract, 4, pp. 103-109, (2006)
[6]  
Dovjak P., Sommeregger U., Otto R., Et al., Polypharmazie in der Kardiologie-ein beachtliches Problem bei Synkopen, QT-Zeit-Verlangerung, Bradykardie und Tachykardie, Wien Med Wochenzeitschr, 160, pp. 264-269, (2010)
[7]  
Elsawy B., Higgins K.E., The geriatric assessment, Am Fam Physician, 83, pp. 48-56, (2011)
[8]  
Gallagher P., O'Mahony D., STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions): Application to acutely ill elderly patients and comparison with Beer's criteria, Age Ageing, 37, pp. 673-679, (2008)
[9]  
Gandhi T.K., Weingart S.N., Borus J., Et al., Adverse drug events in ambulatory care, N Engl J Med, 16, pp. 1556-1564, (2003)
[10]  
Gosch M., Bohmdorfer B., Benvenuti Falger U., Et al., Polypharmazie und Schmerztherapie, Wien Med Wochenzeitschr, 160, pp. 286-292, (2010)