Polymorphous low-grade adenocarcinoma of the tongue: A case report

被引：7

作者：

Gupta R. ^{[1
]}

Gupta K. ^{[1
]}

Gupta R. ^{[1
]}

机构：

[1] Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh

来源：

Journal of Medical Case Reports | / 3卷 / 1期

关键词：

Salivary Gland; Adenoid Cystic Carcinoma; Pleomorphic Adenoma; Lateral Border; Minor Salivary Gland;

D O I：

10.1186/1752-1947-3-9313

中图分类号：

学科分类号：

摘要：

Introduction. Polymorphous low-grade adenocarcinoma is a distinct neoplasm of the salivary gland composed of luminal and non-luminal tumor cells admixed in varying proportions. Its resemblance to lobular carcinoma of the breast had led to its earlier nomenclature of 'terminal duct carcinoma'. Most patients present with an asymptomatic mass in the hard palate. In rare cases, the mass can also occur in the tongue. We report an unusual case of polymorphous low-grade adenocarcinoma at the base of tongue. Case presentation. A 47-year-old Asian Caucasian woman presented with a painless swelling at the right lateral border of the tongue with an intact overlying mucosa. There were no other associated complaints. The lesion was excised and subjected to histopathological examination that revealed an interesting and unusual morphology of polymorphous low-grade adenocarcinoma. Conclusion. Polymorphous low-grade adenocarcinoma is a well-defined entity in the minor salivary glands. Its occurrence in the tongue is rare with very few cases reported in the literature. It is a malignant neoplasm with low aggressiveness and it is thus important to identify and treat it accordingly. © 2009 Gupta et al; licensee BioMed Central Ltd.

引用

共 8 条

[1] Evans H.L., Batsakis J.G., Polymorphous low-grade adenocarcinoma of minor salivary glands: A study of 14 cases of a distinctive neoplasm, Cancer, 53, pp. 935-942, (1984)
[2] Perez-Ordonez B., Linkov I., Huvos A.G., Polymorphous low-grade adenocarcinoma of minor salivary glands: A study of 17 cases with emphasis on cell differentiation, Histopathology, 32, pp. 521-529, (1998)
[3] Tincani A.J., Altemani A., Martins A.S., Barreto G., Valerio J.B., Del Negro A., Arajo P.P., Polymorphous low-grade adenocarcinoma at the base of the tongue: An unusual location, Ear Nose Throat J, 84, pp. 794-795, (2005)
[4] De Diego J.I., Bernaldez R., Prim M.P., Hardisson D., Polymorphous low-grade adenocarcinoma of the tongue, J Laryngol Otol, 110, pp. 700-703, (1996)
[5] Kennedy K.S., Healy K.M., Taylor R.E., Strom C.G., Polymorphous low-grade adenocarcinoma of the tongue, Laryngoscope, 97, pp. 533-536, (1987)
[6] Regezi J.A., Zarbo R.J., Stewart J.C., Courtney R.M., Polymorphous low-grade adenocarcinoma of minor salivary gland: A comparative histologic and immunohistochemical study, Oral Surg Oral Med Oral Pathol, 71, pp. 469-475, (1991)
[7] Anderson C., Krutchkoff D., Pedersen C., Cartun R., Berman M., Polymorphous low-grade adenocarcinoma of minor salivary gland: A clinicopathologic and comparative immunohistochemical study, Mod Pathol, 3, pp. 76-82, (1990)
[8] Brocheriou C., Polymorphous low-grade adenocarcinoma of the minor salivary glands: Seven cases, Arch Anat Cytol Pathol, 40, (1992)

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