Taking BETs on cardiomyocyte differentiation

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Nature Cardiovascular Research | 2024年 / 3卷
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Motivated by a CRISPR screen, in vitro and in vivo studies identified an essential role for the bromodomain and extraterminal domain (BET) family member BRD4 in the differentiation of second heart field progenitors into cardiomyocytes. Single-cell transcriptomic studies showed that BRD4 deficiency affects a specific subset of cardiac progenitor cells.
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页码：265 / 266
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