Value of diffusion-weighted MRI in the differentiation of benign and malign breast lesionsWertigkeit diffusionsgewichteter MRI in der Differenzierung benigner und maligner Läsionen der Brust

被引:0
作者
G. Sonmez
F. Cuce
H. Mutlu
M. Incedayi
E. Ozturk
O. Sildiroglu
M. Velioglu
C.C. Bashekim
E. Kizilkaya
机构
[1] GATA Haydarpasa Teaching Hospital,Department of Radiology
来源
Wiener klinische Wochenschrift | 2011年 / 123卷
关键词
Breast cancer; Breast mass; Magnetic resonance imaging; Diffusion-weighted imaging; Apparent diffusion coefficient;
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摘要
INTRODUCTION: Our purpose was to determine whether diffusion-weighted MR imaging (DWI) could be used in differentiation of benign and malign breast lesions. MATERIALS AND METHODS: 41 women patients were included in the study. 45 lesions were diagnosed by biopsy; 25 (55.5%) of these lesions were malignant and 20 (44.5%) were benign. The apparent diffusion coefficient (ADC) values of these lesions were prospectively compared with their histopathological results. RESULTS: Differentiation of the malignant and benign masses revealed that the threshold value of the ADC was 1.0×10–3 mm2/s, its sensitivity was demonstrated as 95%, specificity as 100%, positive predictive as 100%, negative predictive as 94% and accuracy rate as 97%. CONCLUSIONS: DWI improves diagnostic accuracy of the conventional breast MRI. ADC measurements may be useful for differentiation of the malign and benign masses.
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页码:655 / 661
页数:6
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