Deletion of the HAMP domains from the histidine kinase CaNik1p of Candida albicans or treatment with fungicides activates the MAP kinase Hog1p in S. cerevisiae transformants

被引：0
作者：
Mohammed El-Mowafy
Mahmoud M Bahgat
Ursula Bilitewski
机构：
[1] Helmholtz Centre for Infection Research (HZI),AG Biological Systems Analysis
[2] Mansoura University,Department of Microbiology and Immunology, Faculty of Pharmacy
[3] the National Research Center,Therapeutic Chemistry Department, Immunology and Infectious Diseases Research Group
[4] TWINCORE,Research Group Biomarkers for Infectious Diseases, Institute for Experimental Infection Research
[5] Centre for Experimental and Clinical Infection Research,undefined
来源：
BMC Microbiology | / 13卷
关键词：
Group III histidine kinase; CaNik1p; Point mutations; Protein domains; Fludioxonil; Transformed ; HAMP domains;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 220 条
  • [1] Roeder A(2004)Toll-like receptors as key mediators in innate antifungal immunity Med Mycol 42 485-498
  • [2] Kirschning CJ(2011)Emerging opportunistic yeast infections Lancet Infect Dis 11 142-151
  • [3] Rupec RA(2006)Epidemiology of Candida albicans infections and role of non-Candida-albicans yeasts Curr Drug Targets 7 495-504
  • [4] Schaller M(2009)Epidemiology and outcomes of candidemia in 2019 patients: data from the prospective antifungal therapy alliance registry Clin Infect Dis 48 1695-1703
  • [5] Weindl G(2012)Antifungal resistance and new strategies to control fungal infections Int J Microbiol 2012 713687-288
  • [6] Korting HC(2006)Breakthrough fungemia caused by fluconazole-resistant Candida albicans with decreased susceptibility to voriconazole in patients with hematologic malignancies Haematologica 91 287-4803
  • [7] Miceli MH(2008)Two-component signal transduction proteins as potential drug targets in medically important fungi Infect Immun 76 4795-7247
  • [8] Diaz JA(1999)Roles of three histidine kinase genes in hyphal development and virulence of the pathogenic fungus Candida albicans J Bacteriol 181 7243-1161
  • [9] Lee SA(2003)Whole-genome analysis of two-component signal transduction genes in fungal pathogens Eukaryot Cell 2 1151-588
  • [10] Ruhnke M(2006)Global control of dimorphism and virulence in fungi Science 312 583-159
12345678910