Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones

被引:0
作者
Amy L Beynon
M Rowan Brown
Rhiannon Wright
Mark I Rees
I Martin Sheldon
Jeffrey S Davies
机构
[1] Swansea University,Molecular Neuroscience
[2] Swansea University,Center for Nanohealth
[3] Swansea University,Innate Immunity, Institute of Life Sciences
来源
Journal of Neuroinflammation | / 10卷
关键词
Ghrelin; Interleukin-6; Dopamine; Neurones; Lipopolysaccharide; Parkinson’s disease;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 156 条
[1]  
Kojima M(1999)Ghrelin is a growth-hormone-releasing acylated peptide from stomach Nature 402 656-660
[2]  
Hosoda H(2000)Ghrelin induces adiposity in rodents Nature 407 908-913
[3]  
Date Y(2006)Ghrelin controls hippocampal spine synapse density and memory performance Nat Neurosci 9 381-388
[4]  
Nakazato M(2006)Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite J Clin Invest 116 3229-3239
[5]  
Matsuo H(2006)Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers Mol Endocrinol 20 1772-1785
[6]  
Kangawa K(2008)Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra Exp Neurol 212 532-537
[7]  
Tschöp M(2010)Ghrelin prevents 1-methyl-4-phenylpyridinium ion-induced cytotoxicity through antioxidation and NF-kappaB modulation in MES23.5 cells Exp Neurol 222 25-29
[8]  
Smiley DL(2009)Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism J Neurosci 29 14057-14065
[9]  
Heiman ML(2011)The effects of ghrelin on inflammation and the immune system Mol Cell Endocrinol 340 44-58
[10]  
Diano S(2008)Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways Surgery 143 334-342