Processing mechanism of guanidinoacetate in choroid plexus epithelial cells: conversion of guanidinoacetate to creatine via guanidinoacetate N-methyltransferase and monocarboxylate transporter 12-mediated creatine release into the CSF

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作者
Ryuta Jomura
Shin-ichi Akanuma
Yoshiyuki Kubo
Masanori Tachikawa
Ken-ichi Hosoya
机构
[1] University of Toyama,Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences
[2] Tokushima University,Graduate School of Biomedical Sciences
来源
Fluids and Barriers of the CNS | / 19卷
关键词
Creatine; Guanidinoacetate (GAA); Monocarboxylate transporter (MCT/SLC16A); MCT12 (SLC16A12); Choroid plexus epithelial cells; Blood-cerebrospinal fluid barrier (BCSFB); Guanidinoacetate N-methyltransferase (GAMT);
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