Breaking a temporal barrier: signalling crosstalk regulates the initiation of border cell migration

被引:0
|
作者
Dorothea Godt
Ulrich Tepass
机构
[1] University of Toronto,Dorothea Godt and Ulrich Tepass are in the Department of Cell and Systems Biology
[2] Toronto,undefined
[3] Ontario,undefined
[4] M5S 3G5,undefined
[5] Canada. d.godt@utoronto.ca; u.tepass@utoronto.ca,undefined
[6] u.tepass@utoronto.ca,undefined
来源
Nature Cell Biology | 2009年 / 11卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Correct timing of developmental events is crucial for generating a normal organism. During oogenesis in Drosophila melanogaster, migration of border cells occurs in a defined temporal window and requires Jak/Stat and steroid hormone signalling. The initiation of border-cell migration is now shown to be timed by Jak/Stat-mediated downregulation of the BTB domain transcriptional regulator Abrupt, which acts as a negative regulator of steroid hormone signalling.
引用
收藏
页码:536 / 538
页数:2
相关论文
共 43 条
  • [21] Crosstalk Between Reticular Adherens Junctions and Platelet Endothelial Cell Adhesion Molecule-1 Regulates Endothelial Barrier Function
    Fernandez-Martin, Laura
    Marcos-Ramiro, Beatriz
    Bigarella, Carolina L.
    Graupera, Mariona
    Cain, Robert J.
    Reglero-Real, Natalia
    Jimenez, Anais
    Cernuda-Morollon, Eva
    Correas, Isabel
    Cox, Susan
    Ridley, Anne J.
    Millan, Jaime
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2012, 32 (08) : E90 - U141
  • [22] A Zinc transporter (Catsup) regulates Notch signaling and affects ER homeostasis during Drosophila border cell migration.
    Guo, X.
    Montell, D. J.
    MOLECULAR BIOLOGY OF THE CELL, 2018, 29 (26)
  • [23] Wnt5a-mediated non-canonical Wnt signalling regulates human endothelial cell proliferation and migration
    Cheng, Ching-wen
    Yeh, Ju-ching
    Fan, Tai-Ping
    Smith, Stephen K.
    Charnock-Jones, D. Stephen
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 365 (02) : 285 - 290
  • [24] GTP exchange factor Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation
    Fernandez-Espartero, Cecilia H.
    Ramel, Damien
    Farago, Marganit
    Malartre, Marianne
    Luque, Carlos M.
    Limanovich, Shiran
    Katzav, Shulamit
    Emery, Gregory
    Martin-Bermudo, Maria D.
    JOURNAL OF CELL SCIENCE, 2013, 126 (10) : 2285 - 2293
  • [25] Rab23 regulates cell migration independent of hedgehog signalling in zebrafish: new insight into the Carpenter syndrome phenotype
    Jenkins, Dagan
    Wilkie, Andrew
    MECHANISMS OF DEVELOPMENT, 2009, 126 : S121 - S121
  • [26] Endothelial Cell Secreted Macrophage Migration Inhibitory Factor (mif) Regulates Pericyte Contractility To Decrease Barrier Function
    Pellowe, A. S.
    Sauler, M.
    Liu, R.
    Harris, M. R.
    Calderon, B.
    Zhang, Y.
    Pober, J. S.
    Bucala, R.
    Lee, P. J.
    Gonzalez, A.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195
  • [27] Tousled-like kinase regulates cytokine-mediated communication between cooperating cell types during collective border cell migration
    Xiang, Wenjuan
    Zhang, Dabing
    Montell, Denise J.
    MOLECULAR BIOLOGY OF THE CELL, 2016, 27 (01) : 12 - 19
  • [28] BREAKING THE BARRIER: ADOPTIVE CELLULAR THERAPY HALTS GLIOMA IMMUNOSUPPRESSION BY TARGETING MYELOID-DERIVED SUPPRESSOR CELL MIGRATION AND CELL CYCLE MECHANISMS
    Figg, John
    Francis, Connor
    Jin, Dan
    Reid, Alexandra
    Font, Laura Falceto
    Dean, Bayli DiVita
    Love, Caitland
    Hilferty, David
    Mcdonald, Brianna
    Flores, Catherine
    NEURO-ONCOLOGY, 2024, 26
  • [29] N-Cadherin Regulates Cell Migration Through a Rab5-Dependent Temporal Control of Macropinocytosis
    Wen, Meng-Hsuan
    Wang, Jen-Yeu
    Chiu, Yu-Ting
    Wang, Mei-Pin
    Lee, Sue-Ping
    Tai, Chin-Yin
    TRAFFIC, 2016, 17 (07) : 769 - 785
  • [30] ST3GAL1 regulates cancer cell migration through crosstalk between EGFR and neuropilin-1 signaling
    Fan, Tan-chi
    Yeo, Hui Ling
    Hung, Tsai-Hsien
    Chang, Nai-Chuan
    Tang, Yun-Hsin
    Yu, John
    Chen, Shih-Hsiang
    Yu, Alice L.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2025, 301 (04)