A man with hereditary exostoses and high-grade non-Hodgkin's lymphoma of the bone

被引：0

作者：

K. Neben

M. Werner

L. Bernd

V. Ewerbeck

G. Delling

A. Ho

机构：

[1] Department of Internal Medicine V,

[2] University of Heidelberg,undefined

[3] Hospitalstr. 3,undefined

[4] 69115 Heidelberg,undefined

[5] Germany,undefined

[6] Department of Bone Pathology,undefined

[7] Institute of Pathology,undefined

[8] University of Hamburg,undefined

[9] Martinistr. 52,undefined

[10] 20246 Hamburg,undefined

[11] Germany,undefined

[12] Department of Orthopaedic Surgery,undefined

[13] University of Heidelberg,undefined

[14] Schlierbacher Landstr. 200a,undefined

[15] 69118 Heidelberg,undefined

[16] Germany,undefined

来源：

Annals of Hematology | 2001年 / 80卷

关键词：

Multiple cartilaginous exostoses Non-Hodgkin's lymphoma of the bone;

D O I：

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摘要：

Multiple cartilaginous exostoses (MCE) is an autosomal dominant disorder that can lead to malignant transformation from exostoses to a secondary chondrosarcoma. We present a case report of a 52-year-old man with MCE who had a palpable mass at the left shoulder. At the site of the left proximal humerus, a cartilaginous exostosis was localized, suggesting that the tumor developed by a malignant transformation of an exostosis into a secondary chondrosarcoma. Interestingly, a biopsy showed a diffuse large B-cell lymphoma with Burkitt-like features. To our knowledge, the association of high-grade lymphoma and hereditary exostoses has not been described previously. This case demonstrates that a malignant tumor at the location of a cartilaginous exostosis is not necessarily a chondrosarcoma and that a biopsy is an essential part of the diagnostic work-up.

引用

页码：682 / 684

页数：2