Anti-erythema and anti-edema activities of lactic acid bacteria extracts in mice

被引：1

作者：

Choi J.-S. ^{[1
,2
]}

Jang D.B. ^{[1
]}

Cho H.K. ^{[1
]}

Lee B.-B. ^{[1
]}

Ha Y.-M. ^{[1
]}

Choi I.S. ^{[1
,3
]}

机构：

[1] RIS Center, Industry-Academic Cooperation Foundation, Silla University, 140, Baegyang-daero 700beon-gil, Sasang-gu, Busan

[2] Major in Food Biotechnology, Division of Bioindustry, College of Medical and Life Sciences, Silla University, 140, Baegyang-daero 700beon-gil, Sasang-gu, Busan

[3] Department of Biological Science, Silla University, 140, Baegyangdaero 700beon-gil, Sasang-gu, Busan

来源：

Toxicology and Environmental Health Sciences | 2017年 / 9卷 / 1期

关键词：

Anti-inflammatory effect; Bifidobacterium lactis; Lactic acid bacteria extracts; Mouse;

D O I：

10.1007/s13530-017-0307-3

中图分类号：

学科分类号：

摘要：

We examined the anti-inflammatory activities of 10 lactic acid bacteria extracts, obtained by lysozyme treatment. Among ferments of the 10 species, Bifidobacterium lactis showed the highest anti-erythema (73.4%) and anti-edema (67.1%) effects. When comparing the anti-inflammatory activities of fermented broth and lactic acid bacteria in fermentation broth, the anti-erythema effect (70.4%) of 37.5 μg B. lactis hydrolysate, hydrolyzed enzymatically with 2.0 mg/mL lysozyme, was superior to that of the supernatant (68.5%). The anti-edema effect (74.2%) of 50 μg B. lactis hydrolysate, hydrolyzed enzymatically with 2.0 mg/mL lysozyme, was superior to that of the supernatant (68.5%). These results suggest that B. lactis hydrolysate may be useful as a source of anti-inflammatory agents for dermal applications. © 2017, Korean Society of Environmental Risk Assessment and Health Science and Springer Science+Business Media Dordrecht.

引用

页码：82 / 87

页数：5

共 26 条

[1]

Blandino G., Fazio D., Di Marco R., Probiotics: overview of microbiological and immunological characteristics, Expert. Rev. Anti. Infect. Ther., 6, pp. 497-508, (2008)

[2]

Al-Ghazzewi F.H., Tester R.F., Impact of prebiotics and probiotics on skin health, Benef. Microbes, 5, pp. 99-107, (2014)

[3]

Tomita T., Nagase T., Defensins as a mechanism of host defense and innate immunity, Nippon Ronen Igakkai Zasshi, 38, pp. 440-443, (2001)

[4]

Sang Y., Blecha F., Antimicrobial peptides and bacteriocins: alternatives to traditional antibiotics, Anim. Health Res. Rev., 9, pp. 227-235, (2008)

[5]

Baba H., Et al., Oral intake of Lactobacillus helveticus-fermented milk whey decreased transepidermal water loss and prevented the onset of sodium dodecylsulfateinduced dermatitis in mice, Biosci. Biotechnol. Biochem., 74, pp. 18-23, (2010)

[6]

Won T.J., Et al., Oral administration of Lactobacillus strains from Kimchi inhibits atopic dermatitis in NC/Nga mice, J. Appl. Microbiol., 110, pp. 1195-1202, (2011)

[7]

Kano H., Et al., Oral administration of Lactobacillus delbrueckii subspecies bulgaricus OLL1073R-1 suppresses inflammation by decreasing interleukin-6 responses in a murine model of atopic dermatitis, J. Dairy Sci., 96, pp. 3525-3534, (2013)

[8]

Kim H., Et al., Oral administration of Lactobacillus plantarum lysates attenuates the development of atopic dermatitis lesions in mouse models, J. Microbiol., 53, pp. 47-52, (2015)

[9]

Viljanen M., Et al., Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double-blind placebo-controlled trial, Allergy, 60, pp. 494-500, (2005)

[10]

Ogawa T., Et al., A new symbiotic, Lactobacillus casei subsp. casei together with dextran, reduces murine and human allergic reaction, FEMS Immunol. Med. Microbiol., 46, pp. 400-409, (2006)

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