Topical and systemic medications for the treatment of primary Sjögren's syndrome

被引:0
作者
Manuel Ramos-Casals
Pilar Brito-Zerón
Antoni Sisó-Almirall
Xavier Bosch
Athanasios G. Tzioufas
机构
[1] Sjögren's Syndrome Research Group (AGAUR),Department of Autoimmune Diseases
[2] Laboratory of Autoimmune Diseases Josep Font,Department of Internal Medicine
[3] Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS),Department of Pathophysiology
[4] Hospital Clínic,undefined
[5] University of Barcelona,undefined
[6] Institut Clínic de Medicina i Dermatologia (ICMiD),undefined
[7] Hospital Clínic,undefined
[8] University of Barcelona,undefined
[9] Primary Care Research Group,undefined
[10] IDIBAPS,undefined
[11] University of Barcelona,undefined
[12] CAP Les Corts,undefined
[13] GESCLINIC,undefined
[14] School of Medicine,undefined
[15] University of Athens,undefined
来源
Nature Reviews Rheumatology | 2012年 / 8卷
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摘要
Both sicca and systemic symptoms affect quality of life in patient with Sjögren's syndrome, and their management is complicated by the low level of evidence supporting the available therapeutic options. Here, the authors comprehensively review the data on the efficacy of treatments for the glandular and extraglandular manifestations of this disease. Ramos-Casals and colleagues also recommend treatment approaches tailored to different clinical scenarios that patients with Sjögren's syndrome can present.
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页码:399 / 411
页数:12
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共 283 条
[1]  
Fox RI(2005)Sjögren's syndrome Lancet 366 321-331
[2]  
Kassan SS(2004)Clinical manifestations and early diagnosis of Sjögren syndrome Arch. Intern. Med. 164 1275-1284
[3]  
Moutsopoulos HM(2010)Treatment of primary Sjögren syndrome: a systematic review JAMA 304 452-460
[4]  
Ramos-Casals M(2008)The efficacy of Xialine in patients with Sjögren's syndrome: a single-blind, cross-over study Clin. Oral Investig. 12 165-172
[5]  
Tzioufas AG(2004)Saliva substitute in xerostomic patients with primary Sjögren's syndrome: a single-blind trial Quintessence Int. 35 392-396
[6]  
Stone JH(1992)Comparison between new saliva stimulants in patients with dry mouth: a placebo-controlled double-blind crossover study J. Oral Pathol. Med. 21 376-380
[7]  
Sisó A(2001)Effects of mouthrinses with linseed extract Salinum without/with chlorhexidine on oral conditions in patients with Sjögren's syndrome. A double-blind crossover investigation Gerodontology 18 87-94
[8]  
Bosch X(2000)Clinical evaluation of a commercially available oral moisturizer in relieving signs and symptoms of xerostomia in postirradiation head and neck cancer patients and patients with Sjögren's syndrome J. Otolaryngol. 29 28-34
[9]  
Alpöz E(1996)Treatment of xerostomia with polymer-based saliva substitutes in patients with Sjögren's syndrome Arthritis Rheum. 39 57-63
[10]  
Alves MB(1986)A double-blind crossover trial of CMC- and mucin-containing saliva substitutes Int. J. Oral Maxillofac. Surg. 15 395-400