Phosphorylation of myosin light chains and C-protein in the myocardium of hibernating ground squirrel Citellus undulatus

被引：0

作者：

Malyshev S.L. ^{[1
]}

Osipova D.A. ^{[1
]}

Vikhlyantsev I.M. ^{[1
]}

Podlubnaya Z.A. ^{[2
]}

机构：

[1] Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region

[2] Pushchino State University, Pushchino, Moscow Region

来源：

Biophysics | 2006年 / 51卷 / 5期

基金：

俄罗斯基础研究基金会;

关键词：

C-protein; Hibernation; Myocardium; Myosin regulatory light chain; Phosphorylation;

D O I：

10.1134/S0006350906050265

中图分类号：

学科分类号：

摘要：

A comparative study was made of the extent of phosphorylation of myosin regulatory light chains and C-protein from the left ventricle of the hibernant ground squirrel Citellus undulatus during the periods of hibernation and activity. During hibernation, the light chains were found to be completely dephosphorylated. In active animals, the share of phosphorylated light chains averaged 40-45%. The extent of cardiac C-protein phosphorylation in hibernation was about twice higher than in the active state. Seasonal differences in phosphorylation of the two proteins of ground squirrel myocardium are discussed in the context of adaptation to hibernation. © Nauka/Interperiodica 2006.

引用

页码：822 / 825

页数：3

共 9 条

[1] Seasonal changes in phosphorylation of myosin regulatory light chains and C-protein in myocardium of hibernating ground squirrel Citellus undulatus
Malyshev, S. L.
Osipova, D. A.
Vikhlyantsev, I. M.
Podlubnaya, Z. A.
BIOFIZIKA, 2006, 51 (05): : 929 - 933
[2] Sodium current preserves electrical excitability in the heart of hibernating ground squirrel (Citellus undulatus)
Filatova, Tatiana S.
Kuzmin, Vladislav S.
Guskova, Viktoria O.
Abramochkin, Denis, V
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, 2023, 282
[3] A study of the properties of the C protein from skeletal and cardiac muscles of ground squirrel Citellus undulatus at different stages of the hibernation
Vikhlyantsev, IM
Alekseeva, YA
Shpagina, MD
Udaltsov, SN
Podlubnaya, ZA
BIOFIZIKA, 2002, 47 (04): : 701 - 705
[4] TITIN, MYOSIN LIGHT-CHAINS AND C-PROTEIN IN THE DEVELOPING AND FAILING HUMAN HEART
MORANO, I
HADICKE, K
GROM, S
KOCH, A
SCHWINGER, RHG
BOHM, M
BARTEL, S
ERDMANN, E
KRAUSE, EG
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1994, 26 (03) : 361 - 368
[5] Seasonal changes in the isoform composition of the myosin heavy chains in skeletal muscles of hibernating ground squirrels Spermophilus undulatus
Lazareva M.V.
Trapeznikova K.O.
Vikhlyantsev I.M.
Bobylev A.G.
Klimov A.A.
Podlubnaya Z.A.
Biophysics, 2012, 57 (6) : 764 - 768
[6] Protein kinase C α and ε phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium
Viola Kooij
Nicky Boontje
Ruud Zaremba
Kornelia Jaquet
Cris dos Remedios
Ger J. M. Stienen
Jolanda van der Velden
Basic Research in Cardiology, 2010, 105 : 289 - 300
[7] Protein kinase C α and ε phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium
Kooij, Viola
Boontje, Nicky
Zaremba, Ruud
Jaquet, Kornelia
dos Remedios, Cris
Stienen, Ger J. M.
van der Velden, Jolanda
BASIC RESEARCH IN CARDIOLOGY, 2010, 105 (02) : 289 - 300
[8] Myosin binding protein-C phosphorylation is the principal mediator of protein kinase A effects on thick filament structure in myocardium
Colson, Brett A.
Patel, Jitandrakumar R.
Chen, Peter P.
Bekyarova, Tanya
Abdalla, Mohamed I.
Tong, Carl W.
Fitzsimons, Daniel P.
Irving, Thomas C.
Moss, Richard L.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2012, 53 (05) : 609 - 616
[9] Attenuation of canine cerebral vasospasm after subarachnoid hemorrhage by protein kinase C inhibitors despite augmented phosphorylation of myosin light chain
Nishizawa, S
Obara, K
Koide, M
Nakayama, K
Ohta, S
Yokoyama, T
JOURNAL OF VASCULAR RESEARCH, 2003, 40 (02) : 169 - 178

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