Use of recombinant tissue plasminogen activator in cancer patients with acute stroke

被引:0
作者
Jerome J. Graber
Lakshmi Nayak
Lisa M. DeAngelis
机构
[1] Memorial Sloan-Kettering Cancer Center,Department of Neurology
来源
Journal of Neuro-Oncology | 2012年 / 107卷
关键词
Stroke; Recombinant tissue plasminogen activator; TPA; Cancer; Malignancy; Neoplasm;
D O I
暂无
中图分类号
学科分类号
摘要
People with cancer may be at increased risk for stroke, especially of cardioembolic and large vessel origin. Some clinicians are reluctant to use recombinant tissue plasminogen activator (rTPA) in the cancer population due to safety concerns. We conducted a retrospective review of patients who received rTPA for acute stroke at an academic cancer center. We report six patients with cancer treated with rTPA at our institution, four of whom had early neurologic recovery. Only one of our six patients suffered minor bleeding as a complication of rTPA. Acute stroke in patients with cancer may be treated with rTPA, and active cancer should not be considered an absolute contraindication to rTPA use.
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页码:571 / 573
页数:2
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