Traceable point-like 68Ge/68Ga source with a spherically symmetric positron absorber for PET scanners

被引:0
作者
Tomoyuki Hasegawa
Mio Okamoto
Takahiro Yamada
Hidetake Ishizu
Takahiro Mikamoto
Yasushi Sato
Hiroki Miyatake
Kei Kikuchi
Yusuke Inoue
机构
[1] Kitasato University,School of Allied Health Sciences
[2] Kitasato University,Graduate School of Medical Sciences
[3] Kindai University,Atomic Energy Research Institute
[4] Japan Radioisotope Association,Department of Radiology
[5] National Institute of Advanced Industrial Science and Technology,Department of Diagnostic Radiology
[6] Kitasato University Hospital,undefined
[7] Kitasato University School of Medicine,undefined
来源
Radiological Physics and Technology | 2020年 / 13卷
关键词
PET; Point-like source; Calibration; Quality control;
D O I
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学科分类号
摘要
A novel traceable point-like 68Ge/68Ga source was developed for calibration of positron emission tomography (PET) scanners. The source was equipped with a spherically symmetric acrylic positron absorber. The physical characteristics of photons emitted from the point-like source were evaluated by Monte Carlo simulation, considering possible geometrical uncertainties. The calibration factor of a clinical PET/CT scanner was evaluated using four manufactured point-like sources as a practical application of the point-like source. The results were consistent with that determined by the conventional cross-calibration method. The traceable point-like 68Ge/68Ga source is expected to be a simple and practical tool for determining the calibration factor and evaluating the physical characteristics of PET scanners.
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页码:170 / 176
页数:6
相关论文
共 82 条
[1]  
Eichling JO(1977)Determination of radionuclide concentrations with positron CT scanning (PET): concise communication J Nucl Med 18 845-847
[2]  
Higgins CS(1989)Study on the stability of the calibration and normalization in PET and the influence of drifts on the accuracy of quantification Eur J Nucl Med 15 732-735
[3]  
Ter-Pogossian MM(1989)Quality control procedures in positron tomography Eur J Nucl Med 15 736-740
[4]  
Reist HW(2000)An ionization chamber as a secondary standard for activity Appl Radiat Isot 52 633-636
[5]  
Stadelmann O(2002)Multicenter comparison of calibration and cross calibration of PET scanners J Nucl Med 43 635-639
[6]  
Kleeb W(2011)Quantifying and reducing the effect of calibration error on variability of PET/CT standardized uptake value measurements J Nucl Med 52 218-224
[7]  
Spinks T(2009)Radiation-based quantitative bioimaging at the national institute of standards and technology J Med Phys 34 117-121
[8]  
Jones T(2010)Development of a traceable calibration methodology for solid J Nucl Med 51 448-453
[9]  
Heather J(2014)Ge/ Appl Radiat Isot 87 5-9
[10]  
Gilardi M(2015)Ga sources used as a calibration surrogate for J Nucl Med 56 1453-1457