Molekulare Mechanismen selektiver Autophagie

被引：0
作者：
Krick R. [1 ,2 ]
机构：
[1] Institut für Zellbiochemie, Universitätsmedizin Göttingen, Göttingen
[2] Zentrum Biochemie und Molekulare Zellbiochemie Institut für Zellbiochemie, Georg-August-Universität, Universitätsmedizin Göttingen, Humboldtallee 23, Göttingen
来源：
BIOspektrum | 2018年 / 24卷 / 4期
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D O I：
10.1007/s12268-018-0937-2
中图分类号：
学科分类号：
摘要：
Autophagy is a conserved transport pathway that degrades cytosolic material to generate energy or prevent accumulation of harmful material. Selective autophagy targets a defined cargo for degradation. The key factor Atg8 interacts with multiple proteins in order to execute its functions in vesicles biogenesis during selective autophagy. Therefore, its conjugation to the autophagic membrane is organized by Atg21. We aim for mechanistic insights into the assembly of the different Atg8 complexes. © 2018, Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature.
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页码：404 / 407
页数：3
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