Effect of the leu-enkephalin analog dalargin on DNA synthesis in the myocardium and lingual epithelium of rats in early postnatal ontogeny

被引：0
作者：
E. N. Goncharova
S. S. Timoshin
T. V. Yatsenko
机构：
[1] State Medical Institute,Central Research Laboratory
[2] Siberian Division of the Russian Academy of Medical Sciences,Institute of Maternal and Child Health
来源：
Bulletin of Experimental Biology and Medicine | 1997年 / 123卷
关键词：
dalargin; DNA synthesis; myocardium; epithelium; postnatal ontogeny;
D O I：
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学科分类号：
摘要：
The DNA synthesis is studied in the myocardium and lingual epithelium of 4–5-day-old rats 24 h after a single administration of the leu-enkephalin analog dalargin in a dose of 10 or 100 µg/kg. At 10 µg/kg, dalargin significantly decreases the number of DNA-synthesizing nuclei in the left atrium, while at 100 µg/kg it significantly decreases the number of DNA-synthesizing nuclei in the left atrium and both ventricles. Dalargin does not change the DNA synthesis in the lingual epithelial cells.
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页码：36 / 38
页数：2
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