Distribution of intrachromosomal telomeric sequences (ITS) on Macaca fascicularis (Primates) chromosomes and their implication for chromosome evolution

被引：0

作者：

A. Ruiz-Herrera

F. García

C. Azzalin

E. Giulotto

J. Egozcue

M. Ponsà

M. Garcia

机构：

[1] Departament de Biologia Cel·lular,

[2] Fisiologia i Immunologia,undefined

[3] Universitat Autònoma de Barcelona,undefined

[4] 08193 Barcelona,undefined

[5] Institut de Biotecnologia i Biomedicina (IBB),undefined

[6] Universitat Autònoma de Barcelona,undefined

[7] 08193 Barcelona,undefined

[8] Dipartimento di Genetica e Microbiologia "Adriano Buzzati Traverso",undefined

[9] Universitá di Pavia,undefined

[10] Pavia,undefined

[11] Present address: Departament de Biologia Cel·lular,undefined

[12] Facultat de Medicina,undefined

[13] Universitat Autònoma de Barcelona,undefined

[14] 08193 Cerdanyola del Vallès (Barcelona),undefined

[15] e-mail: Montserrat.Garcia.Caldes@uab.es,undefined

[16] Tel.: +34-93-5811905,undefined

[17] Fax: +34-93-5811025,undefined

来源：

Human Genetics | 2002年 / 110卷

关键词：

Fragile Site; Telomeric Sequence; Pericentric Inversion; Karyotype Evolution; Cytogenet Cell;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The intrachromosomal location of the telomeric sequence in the crab-eating macaque, Macaca fascicularis (F. Cercopithecidae, Catarrhini) has been analysed by fluorescent in situ hybridisation with a long synthetic (TTAGGG)n probe. A total of 237 metaphases was analysed. As expected, all telomeres hybridised with the probe and 90 intrachromosomal loci with different hybridisation frequencies were also detected. The chromosomal location of interstitial telomeric sequences in M. fascicularis and in Homo sapiens was then compared, 37 sites (41.11%) being found to be conserved. Some of these sequences can be derived from rearrangements, such as inversions (MFA13q23) or fusions (MFA2p13 and MFA13p12), that have taken place during karyotype evolution.

引用

页码：578 / 586

页数：8

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