Successful treatment of a pregnant woman with Philadelphia chromosome-positive acute lymphoblastic leukemia

被引：0
作者：
Yuki Nakajima
Hideyuki Kuwabara
Yukako Hattori
Rika Ohshima
Rika Sakai
Masakazu Kitagawa
Naoto Tomita
Yoshiaki Ishigatsubo
Shin Fujisawa
机构：
[1] Yokohama City University Medical Center,Department of Hematology
[2] Kanagawa Cancer Center,Department of Medical Oncology
[3] Yokohama City University Medical Center,Perinatal Center
[4] Yokohama City University Graduate School of Medicine,Department of Internal Medicine and Clinical Immunology
来源：
International Journal of Hematology | 2013年 / 97卷
关键词：
Acute lymphoblastic leukemia; Philadelphia-chromosome positive; Pregnancy; Chemotherapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The management of acute leukemia during pregnancy is challenging. Delays in treatment for acute leukemia can adversely affect maternal prognosis, but chemotherapy during pregnancy may induce severe adverse effects on the fetus. Here, we report a case of a pregnant woman with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) who underwent remission induction therapy and successfully delivered a live infant after chemotherapy. The case is a 36-year-old woman diagnosed with Ph+ALL in the 27th week of pregnancy. She underwent remission induction therapy including daunorubicin, vincristine, cyclophosphamide, and prednisolone. Imatinib was not used in the induction therapy. She delivered the infant after one course of chemotherapy. The infant and the patient are both alive now, without any major complications.
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页码：427 / 429
页数：2
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