Metabolite profiling of the novel anti-cancer agent, plitidepsin, in urine and faeces in cancer patients after administration of 14C-plitidepsin

被引：0

作者：

L. van Andel

H. Rosing

M. M. Tibben

L. Lucas

R. Lubomirov

P. Avilés

A. Francesch

S. Fudio

A. Gebretensae

M. J. X. Hillebrand

J. H. M. Schellens

J. H. Beijnen

机构：

[1] Antoni van Leeuwenhoek/The Netherlands Cancer Institute and MC Slotervaart,Department of Pharmacy and Pharmacology

[2] The Netherlands Cancer Institute,Division of Pharmacology

[3] Pharma Mar,Division of Medical Oncology, Department of Clinical Pharmacology

[4] S.A.,Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Science

[5] The Netherlands Cancer Institute,undefined

[6] Utrecht University,undefined

来源：

Cancer Chemotherapy and Pharmacology | 2018年 / 82卷

关键词：

Aplidin; Plitidepsin; ADME; LC-MS/MS; Total radioactivity; Metabolite profiling;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：441 / 455

页数：14