Metabolite profiling of the novel anti-cancer agent, plitidepsin, in urine and faeces in cancer patients after administration of 14C-plitidepsin

被引：0
|
作者：
L. van Andel
H. Rosing
M. M. Tibben
L. Lucas
R. Lubomirov
P. Avilés
A. Francesch
S. Fudio
A. Gebretensae
M. J. X. Hillebrand
J. H. M. Schellens
J. H. Beijnen
机构：
[1] Antoni van Leeuwenhoek/The Netherlands Cancer Institute and MC Slotervaart,Department of Pharmacy and Pharmacology
[2] The Netherlands Cancer Institute,Division of Pharmacology
[3] Pharma Mar,Division of Medical Oncology, Department of Clinical Pharmacology
[4] S.A.,Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Science
[5] The Netherlands Cancer Institute,undefined
[6] Utrecht University,undefined
来源：
Cancer Chemotherapy and Pharmacology | 2018年 / 82卷
关键词：
Aplidin; Plitidepsin; ADME; LC-MS/MS; Total radioactivity; Metabolite profiling;
D O I：
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中图分类号：
学科分类号：
摘要：
引用
收藏
页码：441 / 455
页数：14
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