Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

被引：0

作者：

Laufey Amundadottir

Peter Kraft

Rachael Z Stolzenberg-Solomon

Charles S Fuchs

Gloria M Petersen

Alan A Arslan

H Bas Bueno-de-Mesquita

Myron Gross

Kathy Helzlsouer

Eric J Jacobs

Andrea LaCroix

Wei Zheng

Demetrius Albanes

William Bamlet

Christine D Berg

Franco Berrino

Sheila Bingham

Julie E Buring

Paige M Bracci

Federico Canzian

Françoise Clavel-Chapelon

Sandra Clipp

Michelle Cotterchio

Mariza de Andrade

Eric J Duell

John W Fox Jr

Steven Gallinger

J Michael Gaziano

Edward L Giovannucci

Michael Goggins

Carlos A González

Göran Hallmans

Susan E Hankinson

Manal Hassan

Elizabeth A Holly

David J Hunter

Amy Hutchinson

Rebecca Jackson

Kevin B Jacobs

Mazda Jenab

Rudolf Kaaks

Alison P Klein

Charles Kooperberg

Robert C Kurtz

Donghui Li

Shannon M Lynch

Margaret Mandelson

Robert R McWilliams

Julie B Mendelsohn

Dominique S Michaud

机构：

[1] Laboratory of Translational Genomics,Division of Cancer Epidemiology and Genetics, Department of Health and Human Services

[2] National Cancer Institute,Division of Cancer Epidemiology and Genetics, Department of Health and Human Services

[3] National Institutes of Health,Department of Epidemiology

[4] National Cancer Institute,Department of Biostatistics

[5] National Institutes of Health,Department of Medical Oncology

[6] Harvard School of Public Health,Department of Medicine

[7] Harvard School of Public Health,Department of Health Sciences Research

[8] Dana-Farber Cancer Institute,Department of Obstetrics and Gynecology

[9] Channing Laboratory,Department of Environmental Medicine

[10] Brigham and Women's Hospital and Harvard Medical School,and Department of Gastroenterology and Hepatology

[11] College of Medicine,Department of Laboratory Medicine/Pathology

[12] Mayo Clinic,Department of Epidemiology and Surveillance Research

[13] New York University School of Medicine,Division of Public Health Sciences

[14] New York University School of Medicine,Department of Medicine and Vanderbilt

[15] New York University Cancer Institute,Ingram Cancer Center

[16] National Institute for Public Health and the Environment (RIVM),Division of Cancer Prevention, Department of Health and Human Services

[17] Bilthoven,Divisions of Preventive Medicine and Aging, Department of Medicine

[18] The Netherlands,Department of Ambulatory Care and Prevention

[19] University Medical Center Utrecht,Department of Epidemiology & Biostatistics

[20] School of Medicine,Division of Cancer Epidemiology

[21] University of Minnesota,Divisions of Aging, Department of Medicine

[22] Prevention and Research Center,Department of Nutrition

[23] Mercy Medical Center,Departments of Oncology

[24] American Cancer Society,Department of Public Health and Clinical Medicine

[25] Fred Hutchinson Cancer Research Center,Department of Gastrointestinal Medical Oncology

[26] Vanderbilt University,Division of Endocrinology, Department of Internal Medicine and Center for Clinical and Translational Science

[27] National Cancer Institute,Department of Oncology

[28] National Institutes of Health,Department of Epidemiology

[29] Etiological Epidemiology and Prevention Unit,Department of Medicine

[30] Fondazione IRCCS Istituto Nazionale dei Tumori di Milano,Division of Cancer Control and Population Sciences, Department of Health and Human Services

[31] MRC Dunn Human Nutrition Unit,Department of Oncology

[32] University of Cambridge,Division of Epidemiology

[33] Brigham and Women's Hospital and Harvard Medical School,Department of Epidemiology and Biostatistics

[34] Harvard Medical School,Department of Cardiology and Department of Clinical Epidemiology

[35] University of California San Francisco,Department of Obstetrics and Gynecology

[36] German Cancer Research Center (DKFZ),Department of Hygiene and Epidemiology

[37] Institut National de la Santé et de la Recherche Médicale (INSERM) and Institut Gustave Roussy,Division of Research

[38] The Johns Hopkins Bloomberg School of Public Health,Department of Chronic Disease Prevention

[39] George W. Comstock Center for Public Health Research and Prevention,Department of Social and Preventive Medicine

[40] Cancer Care Ontario and Dalla Lana School of Public Health,undefined

[41] University of Toronto,undefined

[42] International Agency for Research on Cancer,undefined

[43] College of Human Medicine,undefined

[44] Michigan State University,undefined

[45] Samuel Lunenfeld Research Institute,undefined

[46] Mount Sinai Hospital,undefined

[47] Physicians' Health Study,undefined

[48] Cardiovascular Medicine and Preventive Medicine,undefined

[49] Brigham and Women's Hospital and Harvard Medical School,undefined

[50] Boston,undefined

来源：

Nature Genetics | 2009年 / 41卷

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学科分类号：

摘要：

Stephen Chanock and colleagues report a genome-wide association study of pancreatic cancer. They identify common variants at the ABO blood group locus associated with susceptibility to pancreatic cancer, consistent with previous epidemiological evidence suggesting that individuals with A or B blood types have greater risk of this cancer than individuals with blood type O.

引用

页码：986 / 990

页数：4

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