Three-Component Condensation of 4-Imino-1-Phenylimidazolidin-2-One with Aldehydes and Meldrum's Acid: Synthesis of Imidazo[4,5-b]Pyridine-2,5(4H,6H)-Diones and 5-Substituted 1-Phenylhydantoins

被引:0
作者
Constantine S. Krylov
Andrey N. Komogortsev
Boris V. Lichitsky
Artem N. Fakhrutdinov
Arkady А. Dudinov
Mikhail M. Krayushkin
机构
[1] N. D. Zelinsky Institute of Organic Chemistry,
[2] Russian Academy of Sciences,undefined
来源
Chemistry of Heterocyclic Compounds | 2019年 / 55卷
关键词
aldehydes; imidazo[4,5-; ]pyridine-2,5(4; ,6; )-diones; 4-imino-1-phenylimidazolidin-2-one; Meldrum's acid; 5-substituted 1-phenylhydantoins; three-component condensation;
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摘要
A convenient method for the synthesis of previously unknown imidazo[4,5-b]pyridine-2,5(4H,6H)-diones has been developed, based on a three-component condensation of 4-imino-1-phenylimidazolidin-2-one with aldehydes and Meldrum's acid. The possibility of accessing 5-substituted 1-phenylhydantoins based on the acid hydrolysis of imidazo[4,5-b]pyridine-2,5(4H,6H)-diones was shown.
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页码:851 / 855
页数:4
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  • [1] Rodgers TR(1977)undefined J. Med. Chem. 20 591-undefined
  • [2] LaMontagne MP(1974)undefined Egypt. J. Chem. 17 845-undefined
  • [3] Markovac A(1997)undefined J. Med. Chem. 40 602-undefined
  • [4] Ash AB(1994)undefined Biosci., Biotechnol., Biochem. 58 265-undefined
  • [5] El-Kerdawy MM(1950)undefined Chem. Rev. 46 403-undefined
  • [6] Tantawy AS(2012)undefined Adv. Drug Delivery Rev. 64 887-undefined
  • [7] Abououf AA(1983)undefined Biomed. Res. 4 83-undefined
  • [8] Brown ML(1975)undefined Br. J. Anaesth. 47 62-undefined
  • [9] Brown GB(1982)undefined Anesthesiology 56 254-undefined
  • [10] Brouillette WJ(1992)undefined Science 256 789-undefined