Comprehensive genetic testing combined with citizen science reveals a recently characterized ancient MC1R mutation associated with partial recessive red phenotypes in dog

被引:9
作者
Heidi Anderson
Leena Honkanen
Päivi Ruotanen
Julia Mathlin
Jonas Donner
机构
[1] Wisdom Health,
来源
Canine Medicine and Genetics | / 7卷 / 1期
关键词
Ancient; Canine; Dog; Coat color; Domino; Grizzle; Pheomelanin; Eumelanin; MC1R; Reduced-function variant;
D O I
10.1186/s40575-020-00095-7
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 250 条
[41]  
Dolinoy DC(2004)Anesthetic requirement is increased in redheads Anesthesiology. 101 279-20
[42]  
Michaud EJ(2005)Increased sensitivity to thermal pain and reduced subcutaneous lidocaine efficacy in redheads Anesthesiology. 102 509-149
[43]  
van Vugt MJ(2005)Melanocortin-1 receptor gene variants affect pain and μ-opioid analgesia in mice and humans J Med Genet 42 583-undefined
[44]  
Bultman SJ(2010)Involvement of the melanocortin-1 receptor in acute pain and pain of inflammatory but not neuropathic origin PLoS One 5 1-undefined
[45]  
Sweet HO(2013)A Copy Number Variant at the KITLG Locus Likely Confers Risk for Canine Squamous Cell Carcinoma of the Digit PLoS Genet 9 e1003409-undefined
[46]  
Davisson MT(2016)Genetic panel screening of nearly 100 mutations reveals new insights into the breed distribution of risk variants for canine hereditary disorders PLoS One 11 1-undefined
[47]  
Woychik RP(2018)Frequency and distribution of 152 genetic disease variants in over 100,000 mixed breed and purebred dogs PLoS Genet 14 1-undefined
[48]  
Dreger DL(1951)Note on exact treatment of contingency, goodness of fit and other problems of significance Biometrika. 38 141-undefined
[49]  
Anderson H(undefined)undefined undefined undefined undefined-undefined
[50]  
Donner J(undefined)undefined undefined undefined undefined-undefined