Comprehensive genetic testing combined with citizen science reveals a recently characterized ancient MC1R mutation associated with partial recessive red phenotypes in dog

被引:9
作者
Heidi Anderson
Leena Honkanen
Päivi Ruotanen
Julia Mathlin
Jonas Donner
机构
[1] Wisdom Health,
来源
Canine Medicine and Genetics | / 7卷 / 1期
关键词
Ancient; Canine; Dog; Coat color; Domino; Grizzle; Pheomelanin; Eumelanin; MC1R; Reduced-function variant;
D O I
10.1186/s40575-020-00095-7
中图分类号
学科分类号
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[1]  
Dürig N(2018)Two MC1R loss-of-function alleles in cream-coloured Australian Cattle Dogs and white Huskies Anim Genet 49 284-290
[2]  
Letko A(2000)Melanocortin 1 receptor variation in the domestic dog Mamm Genome 11 24-30
[3]  
Lepori V(2010)A new mutation in MC1R explains a coat color phenotype in 2 “old” breeds: Saluki and Afghan Hound J Hered 101 644-649
[4]  
Hadji Rasouliha S(2003)MCIR Studies in Dogs with Melanistic Mask or Brindle Patterns J Hered 94 69-73
[5]  
Loechel R(2000)Identification of a premature stop codon in the melanocyte-stimulating hormone receptor gene (MC1R) in Labrador and Golden retrievers with yellow coat colour Anim Genet 31 194-199
[6]  
Kehl A(2019)True Colors: Commercially-acquired morphological genotypes reveal hidden allele variation among dog breeds, informing both trait ancestry and breed potential PLoS One 14 1-24
[7]  
Newton JM(2004)Characterization of the dog Agouti gene and a nonagouti mutation in German Shepherd Dogs Mamm Genome 15 798-808
[8]  
Wilkie AL(2005)Association of an Agouti allele with fawn or sable coat color in domestic dogs Mamm Genome 16 262-272
[9]  
He L(2011)A SINE Insertion Causes the Black-and-Tan and Saddle Tan Phenotypes in Domestic Dogs J Hered 104 399-406
[10]  
Jordan SA(2008)The agouti mouse model: An epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome Nutr Rev 66 7-11