Utilize polygenic risk score to enhance fracture risk estimation and improve the performance of FRAX in patients with osteoporosis

被引:0
作者
Jian-Jiun Chen
I-Chieh Chen
Chia-Yi Wei
Shih-Yi Lin
Yi-Ming Chen
机构
[1] Taipei Veterans General Hospital, Department of Orthopedics
[2] Taichung Veterans General Hospital,Department of Medical Research
[3] Taichung Veterans General Hospital,Center for Geriatrics and Gerontology
[4] National Chung-Hsing University,Department of Post
[5] National Yang-Ming Chiao Tung University,Baccalaureate Medicine, College of Medicine
[6] Taichung Veterans General Hospital,School of Medicine
[7] Chung-Hsing University,Division of Allergy, Immunology and Rheumatology
[8] National Chung Hsing University,Institute of Biomedical Science and Rong
来源
Archives of Osteoporosis | / 18卷
关键词
Osteoporosis; Fracture; Polygenic risk score; FRAX; Fracture risk assessment;
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[1]  
Johnell O(2006)An estimate of the worldwide prevalence and disability associated with osteoporotic fractures Osteoporos Int 17 1726-1733
[2]  
Kanis JA(2022)The clinician's guide to prevention and treatment of osteoporosis Osteoporos Int 33 2049-2102
[3]  
LeBoff MS(2014)Clinician's guide to prevention and treatment of osteoporosis Osteoporos Int 25 2359-2381
[4]  
Cosman F(2009)Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women Jama 301 513-521
[5]  
Bliuc D(2014)The global burden attributable to low bone mineral density Ann Rheum Dis 73 1635-1645
[6]  
Sànchez-Riera L(2010)Osteoporosis: impact on health and economics Nat Rev Rheumatol 6 99-105
[7]  
Harvey N(2005)Identification of high-risk individuals for hip fracture: a 14-year prospective study J Bone Miner Res 20 1921-1928
[8]  
Dennison E(2007)Single-site vs multisite bone density measurement for fracture prediction Arch Intern Med 167 1641-1647
[9]  
Cooper C(2005)Assessment of fracture risk Osteoporos Int 16 581-589
[10]  
Nguyen ND(2015)The accuracy of osteoporotic fracture risk prediction tools: a systematic review and meta-analysis Ann Rheum Dis 74 1958-1967