Chromatin remodelling and DNA replication: from nucleosomes to loop domains

被引:0
|
作者
Caroline Demeret
Yegor Vassetzky
Marcel Méchali
机构
[1] Institute of Human Genetics,
[2] CNRS,undefined
[3] Institut Pasteur,undefined
来源
Oncogene | 2001年 / 20卷
关键词
chromatin remodelling; DNA replication; DNA loop domains;
D O I
暂无
中图分类号
学科分类号
摘要
Organization of DNA into chromatin is likely to participate in the control of the timing and selection of DNA replication origins. Reorganization of the chromatin is carried out by chromatin remodelling machines, which may affect the choice of replication origins and efficiency of replication. Replication itself causes a profound rearrangement in the chromatin structure, from nucleosomes to DNA loop domains, allowing to retain or switch an epigenetic state. The present review considers the effects of chromatin remodelling on replication and vice versa.
引用
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页码:3086 / 3093
页数:7
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