Effect of Xymedon on Cell Survival in the System Sensory Neuron Schwann Cell

被引：0
作者：
I. S. Raginov
Yu. A. Chelyshev
T. F. Shagidullin
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来源：
Bulletin of Experimental Biology and Medicine | 2001年 / 131卷
关键词：
neuron; Schwann cell; regeneration; xymedon;
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摘要：
Pyrimidine derivative xymedon inhibits neuronal death in L4-L5 spinal ganglia 30 days after ligation of rat sciatic nerve. After treatment with xymedon the number of neurons on the operated side decreased by 22.1% compared to that on the contralateral side, while in the control group this parameter decreased by 28.7%. At the same terms, the number of Schwann cells on the operated side after xymedon injection increased by 27.7% in comparison with that on the contralateral side, while in the control group this parameter decreased by 57.3%.
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页码：229 / 230
页数：1
相关论文
共 29 条
  • [1] Raginov I. S.(1997)undefined Ros. Morfol. Vedomosti 1 120-126
  • [2] Khafiz'yanova R. K.(2000)undefined Byull. Eksp. Biol. Med. 129 256-259
  • [3] Vafin A. Y.(2000)undefined Uspekchi Fiziol. Nauk 31 54-69
  • [4] Chelyshev Y. A.(2000)undefined Eksp. Klin. Farmakol. 63 17-19
  • [5] Raginov I. S.(1997)undefined J. Neurosci. 17 1642-1659
  • [6] Chelyshev Y. A.(1995)undefined Neuroreport 9 1029-1032
  • [7] Khafizyanova R. K.(1997)undefined Mol. Neurobiol 14 67-116
  • [8] Chelyshev Y. A.(2000)undefined Lakartidningen 97 3168-3173
  • [9] Saitkulov K. I.(1999)undefined Ann. N. Y. Acad. Sci. 883 109-115
  • [10] Chelyshev Y. A.(1993)undefined Curr. Opin Neurobiol. 3 683-693
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