Endothelial protein C receptor polymorphisms and risk of severe sepsis in critically ill patients

[1] Angus DC(2001)Epidemiology of sepsis: an update Crit Care Med 29 S109-S116

[2] Wax RS(2010)The surviving sepsis campaign: results of an international guideline-based performance improvement program targeting severe sepsis Intensive Care Med 36 222-231

[3] Levy MM(2011)Impact of albumin compared to saline on organ function and mortality of patients with severe sepsis Intensive Care Med 37 86-96

[4] Dellinger RP(1989)The septic syndrome. Definition and clinical implications Crit Care Clin 5 1-8

[5] Townsend SR(2013)Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock Intensive Care Med 39 165-228

[6] Linde-Zwirble WT(1989)The roles of protein C and thrombomodulin in the regulation of blood coagulation J Biol Chem 264 4743-4746

[7] Marshall JC(2005)Recombinant human activated protein C upregulates cyclooxygenase-2 expression in endothelial cells via binding to endothelial cell protein C receptor and activation of protease-activated receptor-1 Thromb Haemost 93 743-750

[8] Bion J(2007)Activated protein C mutant with minimal anticoagulant activity, normal cytoprotective activity, and preservation of thrombin activable fibrinolysis inhibitor-dependent cytoprotective functions J Biol Chem 282 33022-33033

[9] Schorr C(1996)The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex Proc Natl Acad Sci USA 93 10212-10216

[10] Artigas A(2002)Distribution of endothelial cell protein C/activated protein C receptor (EPCR) during mouse embryo development Thromb Haemost 88 259-266

[1] Angus DC(2001)Epidemiology of sepsis: an update Crit Care Med 29 S109-S116

[2] Wax RS(2010)The surviving sepsis campaign: results of an international guideline-based performance improvement program targeting severe sepsis Intensive Care Med 36 222-231

[3] Levy MM(2011)Impact of albumin compared to saline on organ function and mortality of patients with severe sepsis Intensive Care Med 37 86-96

[4] Dellinger RP(1989)The septic syndrome. Definition and clinical implications Crit Care Clin 5 1-8

[5] Townsend SR(2013)Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock Intensive Care Med 39 165-228

[6] Linde-Zwirble WT(1989)The roles of protein C and thrombomodulin in the regulation of blood coagulation J Biol Chem 264 4743-4746

[7] Marshall JC(2005)Recombinant human activated protein C upregulates cyclooxygenase-2 expression in endothelial cells via binding to endothelial cell protein C receptor and activation of protease-activated receptor-1 Thromb Haemost 93 743-750

[8] Bion J(2007)Activated protein C mutant with minimal anticoagulant activity, normal cytoprotective activity, and preservation of thrombin activable fibrinolysis inhibitor-dependent cytoprotective functions J Biol Chem 282 33022-33033

[9] Schorr C(1996)The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex Proc Natl Acad Sci USA 93 10212-10216

[10] Artigas A(2002)Distribution of endothelial cell protein C/activated protein C receptor (EPCR) during mouse embryo development Thromb Haemost 88 259-266