Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R

被引:0
作者
Konrad Wilhelm
Jayanthi Ganesan
Tobias Müller
Christoph Dürr
Melanie Grimm
Andreas Beilhack
Christine D Krempl
Stephan Sorichter
Ulrike V Gerlach
Eva Jüttner
Alf Zerweck
Frank Gärtner
Patrizia Pellegatti
Francesco Di Virgilio
Davide Ferrari
Neeraja Kambham
Paul Fisch
Jürgen Finke
Marco Idzko
Robert Zeiser
机构
[1] Freiburg University Medical Center,Department of Hematology and Oncology
[2] Albert-Ludwigs-University,Department of Pneumology
[3] Freiburg University Medical Center,Department of Biology
[4] Albert-Ludwigs-University,Department of Internal Medicine II and Interdisciplinary Center for Clinical Research
[5] Albert-Ludwigs-University,Department of Pathology
[6] University Hospital of Würzburg,Department of Experimental and Diagnostic Medicine
[7] Institute of Virology and Immunobiology,Department of Pathology
[8] Julius-Maximilian University,undefined
[9] Freiburg University Medical Center,undefined
[10] Albert-Ludwigs-University,undefined
[11] Section of General Pathology,undefined
[12] Interdisciplinary Center for the Study of Inflammation,undefined
[13] University of Ferrara,undefined
[14] Stanford University School of Medicine,undefined
来源
Nature Medicine | 2010年 / 16卷
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摘要
By acting on the P2X7 receptor, ATP released upon cell damage functions as a danger signal to promote acute graft-versus-host disease after bone marrow transplantation in mice.
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页码:1434 / 1438
页数:4
相关论文
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