In vivo molecular imaging in preclinical research

被引：0
作者：
Su Jin Kim
Ho-Young Lee
机构：
[1] Seoul National University Bundang Hospital,Department of Nuclear Medicine
[2] Seoul National University College of Medicine,Department of Nuclear Medicine
来源：
Laboratory Animal Research | / 38卷
关键词：
In vivo Molecular Imaging; Fluorescence; Bioluminescence; Computed tomography; PET/CT; SPECT/CT; Probe; Mouse; Small animal imaging;
D O I：
暂无
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学科分类号：
摘要：
In vivo molecular imaging is a research field in which molecular biology and advanced imaging techniques are combined for imaging molecular-level biochemical and physiological changes that occur in a living body. For biomolecular imaging, the knowledge of molecular biology, cell biology, biochemistry, and physiology must be applied. Imaging techniques such as fluorescence, luminescence, single-photon emission computed tomography (SPECT), positron emission tomography (PET), computed tomography (CT), and magnetic resonance imaging (MRI) are used for biomolecular imaging. These imaging techniques are used in various fields, i.e., diagnosis of various diseases, development of new drugs, development of treatments, and evaluation of effects. Moreover, as biomolecular imaging can repeatedly acquire images without damaging biological tissues or sacrificing the integrity of objects, changes over time can be evaluated.
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  • [1] Sosnovik DE(2022)Biomedical imaging in experimental models of cardiovascular disease Circ Res 130 1851-68
  • [2] Scherrer-Crosbie M(2016)Molecular imaging of small animals Med Phys 43 3208-9
  • [3] Zweit J(2022)Monitoring immune cell function hhrough optical imaging: a review highlighting transgenic mouse models Mol Imaging Biol 24 250-63
  • [4] Gobalakrishnan S(2021)Super-resolution fluorescence microscopy methods for assessing Mouse biology Curr Protoc 1 e224-91
  • [5] Chawda C(2020)Opportunities for persistent luminescent nanoparticles in luminescence imaging of biological systems and photodynamic therapy Nanomater 10 2015-109
  • [6] McMorrow R(2009)Small animal imaging with multi-pinhole SPECT Methods 48 83-84
  • [7] Gaspar N(2021)TSPO imaging in animal models of brain diseases Eur J Nucl Med Mol Imaging 49 77-13
  • [8] Zambito G(2003)Micro-PET imaging and small animal models of disease Curr Opin Immunol 15 378-9
  • [9] Mezzanotte L(2010)Application of micro-CT in small animal imaging Methods 50 2-80
  • [10] Valli J(2002)Micro-CT in small animal and specimen imaging Trends Biotechnol 20 34-420
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