Organic solvent effects in reversed-phase liquid chromatography in relation to column testing

被引：0
作者：
K. Le Mapihan
J. Vial
A. Jardy
机构：
[1] UMR 7121,Laboratoire Environnement et Chimie Analytique
[2] Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris 10,undefined
来源：
Chromatographia | 2003年 / 57卷
关键词：
Column liquid chromatography; Column testing; Solvent effect; Neutral and basic compounds;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The solvent effects during RPLC column characterization was evalauted. A test derived from that of Tanaka was performed using both methanol and acetonitrile as organic modifier. Neutral and basic solutes were used to assess the solvent impact on the chromatographic properties of stationary phases. A cross-interaction was often observed between the column and the solvent which means that both the choice of column and solvent must be taken into account during characetrization.
引用
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页码：S163 / S170
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