Long non-coding RNAs regulate drug resistance in cancer

被引:0
作者
Kaisheng Liu
Lin Gao
Xiaoshi Ma
Juan-Juan Huang
Juan Chen
Leli Zeng
Charles R. Ashby
Chang Zou
Zhe-Sheng Chen
机构
[1] The First Affiliated Hospital of Southern University of Science and Technology,Department of Physics
[2] The Second Clinical Medical College of Jinan University,College of Pharmacy and Health Sciences
[3] Shenzhen People’s Hospital,Tomas Lindahl Nobel Laureate Laboratory, Research Centre, The Seventh Affiliated Hospital
[4] Technical University of Munich,undefined
[5] St. John’s University,undefined
[6] Queens,undefined
[7] Sun Yat-sen University,undefined
来源
Molecular Cancer | / 19卷
关键词
Cancer; Drug resistance; Long non-coding RNAs;
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摘要
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various mechanisms. Over the last decade, it has been reported that 1ong noncoding RNAs (lncRNAs) can mediate carcinogenesis and drug resistance/sensitivity in cancer cells. This article reviews, in detail, recent studies regarding the roles of lncRNAs in mediating drug resistance.
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[1]  
Bray F(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 68 394-424
[2]  
Ferlay J(2017)Frailty and cancer: implications for oncology surgery, medical oncology, and radiation oncology CA Cancer J Clin 67 362-377
[3]  
Soerjomataram I(2018)Molecular mechanisms of drug resistance in ovarian cancer J Cell Physiol 233 4546-4562
[4]  
Siegel RL(2015)Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp Cancer Cell Int 15 71-753
[5]  
Torre LA(2014)Poised epigenetic states and acquired drug resistance in cancer Nat Rev Cancer 14 747-395
[6]  
Jemal A(2015)Oncogenes associated with drug resistance in ovarian cancer J Cancer Res Clin Oncol 141 381-641
[7]  
Ethun CG(2009)Evolution and functions of long noncoding RNAs Cell 136 629-268
[8]  
Bilen MA(2011)The functional role of long non-coding RNA in human carcinomas Mol Cancer 10 38-3948
[9]  
Jani AB(2015)APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p Nat Commun 6 6779-2487
[10]  
Maithel SK(2014)The functional role of long non-coding RNAs and epigenetics Biol Proced Online 16 11-112