A structural interpretation of the effect of GC-content on efficiency of RNA interference

被引:0
|
作者
Chi Yu Chan
C Steven Carmack
Dang D Long
Anil Maliyekkel
Yu Shao
Igor B Roninson
Ye Ding
机构
[1] Wadsworth Center,New York State Department of Health
[2] Ordway Research Institute,Cancer Center
[3] University of Illinois at Chicago,Department of Molecular Genetics
来源
关键词
Partial Correlation Analysis; RNAi Activity; RNAi Machinery; RNAi Efficiency; Target Accessibility;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Genomic Legacies of Ancient Adaptation Illuminate GC-Content Evolution in Bacteria
    Teng, Wenkai
    Liao, Bin
    Chen, Mengyun
    Shu, Wensheng
    MICROBIOLOGY SPECTRUM, 2023, 11 (01):
  • [22] Different Modes of Hoechst 33258 Binding with Different GC-content DNAs
    Vardevanyan, Poghos O.
    Antonyan, Ara P.
    Karapetian, Ruzanna A.
    Parsadanyan, Marine A.
    Shahinyan, Mariam A.
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2009, 26 (06): : 878 - 878
  • [23] A Potential Interpretation of RNA Interference and GC Island Modification in Progressive Colorectal Cancer Suppression
    Al-Jumaili, Miqdam M. Obaid
    BIOMEDICAL AND BIOTECHNOLOGY RESEARCH JOURNAL, 2023, 7 (03): : 425 - 431
  • [24] SV-Bay: structural variant detection in cancer genomes using a Bayesian approach with correction for GC-content and read mappability
    Iakovishina, Daria
    Janoueix-Lerosey, Isabelle
    Barillot, Emmanuel
    Regnier, Mireille
    Boeva, Valentina
    BIOINFORMATICS, 2016, 32 (07) : 984 - 992
  • [25] Genome-Wide Search for Local DNA Segments with Anomalous GC-Content
    Ilatovskiy, Andrey
    Petukhov, Michael
    JOURNAL OF COMPUTATIONAL BIOLOGY, 2009, 16 (04) : 555 - 564
  • [26] GC-Content Evolution in Bacterial Genomes: The Biased Gene Conversion Hypothesis Expands
    Lassalle, Florent
    Perian, Severine
    Bataillon, Thomas
    Nesme, Xavier
    Duret, Laurent
    Daubin, Vincent
    PLOS GENETICS, 2015, 11 (02): : 1 - 20
  • [27] Biased Gene Conversion and GC-Content Evolution in the Coding Sequences of Reptiles and Vertebrates
    Figuet, Emeric
    Ballenghien, Marion
    Romiguier, Jonathan
    Galtier, Nicolas
    GENOME BIOLOGY AND EVOLUTION, 2015, 7 (01): : 240 - 250
  • [28] Relationship between gene expression and GC-content in mammals:: statistical significance and biological relevance
    Sémon, M
    Mouchiroud, D
    Duret, L
    HUMAN MOLECULAR GENETICS, 2005, 14 (03) : 421 - 427
  • [29] Efficient Cloning and Sequence Validation of Repetitive and High GC-Content Short Hairpin RNAs
    Chilamkurthy, Ramadevi
    White, Adam A. A.
    Pater, Adrian A. A.
    Jensik, Philip J. J.
    Gagnon, Keith T. T.
    HUMAN GENE THERAPY, 2022, 33 (15-16) : 829 - 839
  • [30] Linear and nonlinear constructions of DNA codes with Hamming distance d and constant GC-content
    Smith, Derek H.
    Aboluion, Niema
    Montemanni, Roberto
    Perkins, Stephanie
    DISCRETE MATHEMATICS, 2011, 311 (13) : 1207 - 1219