Pulse transit time as a derived noninvasive mean to monitor arterial distensibility changes in children

被引:0
作者
J Y A Foo
S J Wilson
G Williams
M-A Harris
D Cooper
机构
[1] School of Information Technology and Electrical Engineering,Department of Respiratory and Sleep Medicine
[2] University of Queensland,undefined
[3] St Lucia Campus,undefined
[4] Mater Children's Hospital,undefined
来源
Journal of Human Hypertension | 2005年 / 19卷
关键词
arterial distensibility; pulse wave velocity; pulse transit time; continuous monitoring; blood pressure;
D O I
暂无
中图分类号
学科分类号
摘要
Changes in arterial distensibility have been widely used to identify the presence of cardiovascular abnormalities like hypertension. Pulse wave velocity (PWV) has shown to be related to arterial distensibility. However, the lack of suitable techniques to measure PWV nonintrusively has impeded its clinical usefulness. Pulse transit time (PTT) is a noninvasive technique derived from the principle of PWV. PTT has shown its capabilities in cardiovascular and cardiorespiratory studies in adults. However, no known study has been conducted to understand the suitability and utility of PTT to estimate PWV in children. Two computational methods to derive PWV from PTT values obtained from 23 normotensive Caucasian children (19 males, aged 5–12 years old) from their finger and toe were conducted. Furthermore, the effects of adopting different postures on the PWV derivations were investigated. Statistical analyses were performed in comparison with two previous PWV studies conducted on children. Results revealed that PWV derived from the upper limb correlated significantly (P<0.05) regardless of computing methods or postures adopted. The findings here suggest that PTT measurement can be used as a convenient and noninvasive surrogate measure of derived PWV in prolonged clinical studies, especially on younger or less cooperative children. Furthermore, the simple set-up and noninvasive nature of PTT can promote its usefulness in ambulatory monitoring.
引用
收藏
页码:723 / 729
页数:6
相关论文
共 48 条
[1]  
Avolio AP(1983)Effects of aging on changing arterial compliance and left ventricular load in a northern Chinese urban community Circulation 68 50-58
[2]  
Cheung YF(2002)Arterial distensibility in children and teenagers: Normal evolution and the effect of childhood vasculitis Arch Dis Child 87 348-351
[3]  
Senzaki H(2002)Age-associated changes in arterial elastic properties in children Eur J Pediatr 161 547-551
[4]  
Martin H(2000)Impaired endothelial function and increased carotid stiffness in 9-year-old children with low birthweight Circulation 102 2739-2744
[5]  
Hu J(2003)Birth weight impacts on wave reflections in children and adolescents Hypertension 41 646-650
[6]  
Gennser G(2004)Home blood pressure measurement: validation of the Braun BP 2550 (UG) monitor according to the ESH International Protocol Blood Press Monit 9 53-58
[7]  
Norman M(2004)Progress on the development of the MediWatch ambulatory blood pressure monitor and related devices Blood Press Monit 9 149-165
[8]  
Lurbe J(1998)A noninvasive method to estimate pulse wave velocity in arteries locally by means of ultrasound Ultrasound Med Biol 24 1325-1335
[9]  
Nolly H(2004)Pressure pulse velocity is related to the longitudinal elastic properties of the artery Physiol Meas 25 1397-1403
[10]  
Ng KG(1999)Pulse transit time: an appraisal of potential clinical applications Thorax 54 452-458