Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis

被引：0
|
作者：
A Matakidou
R el Galta
M F Rudd
E L Webb
H Bridle
T Eisen
R S Houlston
机构：
[1] Section of Cancer Genetics,Department of Oncology
[2] Institute of Cancer Research,undefined
[3] University of Cambridge,undefined
来源：
British Journal of Cancer | 2007年 / 96卷
关键词：
lung cancer; FGFR4; Gly388Arg polymorphism; prognosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The Gly388Arg polymorphism in the fibroblast growth factor receptor 4 (FGFR4) gene has been reported to influence prognosis in a wide variety of cancer types. To determine whether Gly388Arg is a marker for lung cancer prognosis, we genotyped 619 lung cancer patients with incident disease and examined the relationship between genotype and overall survival. While we employed a comprehensive set of statistical tests, including those sensitive to the detection of differences in early survival, our data provide little evidence to support the tenet that the FGFR4 Gly388Arg polymorphism is a clinically useful marker for lung cancer prognosis.
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页码：1904 / 1907
页数：3
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